OTOA 抗体 (AA 231-330)
Quick Overview for OTOA 抗体 (AA 231-330) (ABIN1386386)
抗原
See all OTOA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 231-330
-
交叉反应
- 小鼠
-
预测反应
- Human,Rat
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human OTOA/DFNB22
-
亚型
- IgG
-
-
anti-Otoancorin (OTOA) (AA 27-124) antibody
OTOA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-Otoancorin (OTOA) (AA 92-120), (N-Term) antibodyOTOA 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB28372 unconjugated
anti-Otoancorin (OTOA) (AA 99-127), (N-Term) antibodyOTOA 适用: 小鼠, 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- OTOA (Otoancorin (OTOA))
-
别名
- OTOA/DFNB22
-
背景
-
Synonyms: Cancer/testis antigen 108, CT108, Deafness, autosomal recessive 22, DFNB22, OTOA, OTOAN_HUMAN, Otoancorin.
Background: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.
-
基因ID
- 146183
-
UniProt
- Q7RTW8
-
途径
- Sensory Perception of Sound
抗原
-
