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OTOA 抗体 (AA 231-330)

This anti-OTOA antibody is a 兔 多克隆 antibody detecting OTOA in WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 和 ICC. Suitable for 小鼠.
产品编号 ABIN1386386
发货至: 中国

Quick Overview for OTOA 抗体 (AA 231-330) (ABIN1386386)

抗原

See all OTOA 抗体
OTOA (Otoancorin (OTOA))

适用

  • 24
  • 4
小鼠

宿主

  • 24
  • 1

克隆类型

  • 24
  • 1
多克隆

标记

  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This OTOA antibody is un-conjugated

应用范围

  • 25
  • 12
  • 12
  • 10
  • 8
  • 5
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
  • 抗原表位

    • 14
    • 8
    • 3
    • 2
    • 1
    AA 231-330

    交叉反应

    小鼠

    预测反应

    Human,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human OTOA/DFNB22

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    OTOA (Otoancorin (OTOA))

    别名

    OTOA/DFNB22

    背景

    Synonyms: Cancer/testis antigen 108, CT108, Deafness, autosomal recessive 22, DFNB22, OTOA, OTOAN_HUMAN, Otoancorin.

    Background: Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.

    基因ID

    146183

    UniProt

    Q7RTW8

    途径

    Sensory Perception of Sound
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