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COPS2 抗体

COPS2 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386249
发货至: 中国
  • 抗原 See all COPS2 抗体
    COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
    适用
    • 55
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    • 4
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 52
    • 2
    • 1
    克隆类型
    • 53
    • 2
    多克隆
    标记
    • 27
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    This COPS2 antibody is un-conjugated
    应用范围
    • 54
    • 26
    • 26
    • 12
    • 11
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human COPS2/TRIP15
    亚型
    IgG
    Top Product
    Discover our top product COPS2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
    别名
    COPS2 (COPS2 产品)
    别名
    COPS2 antibody, ALIEN antibody, CSN2 antibody, SGN2 antibody, TRIP15 antibody, wu:fc05f05 antibody, wu:fc06g10 antibody, wu:fc60f04 antibody, wu:fl94f12 antibody, zgc:86624 antibody, csn2 antibody, Tb03.48O8.600 antibody, Trip15 antibody, AI315723 antibody, C85265 antibody, Csn2 antibody, Sgn2 antibody, alien-like antibody, ATCSN2 antibody, CONSTITUTIVE PHOTOMORPHOGENIC 12 antibody, COP12 antibody, FUSCA 12 antibody, T20P8.4 antibody, T20P8_4 antibody, COP9 signalosome subunit 2 antibody, COP9 signalosome subunit 2 L homeolog antibody, COP9 signalosome complex subunit 2 antibody, COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) antibody, proteasome family protein antibody, COPS2 antibody, cops2 antibody, cops2.L antibody, Tb927.3.2320 antibody, AOR_1_576084 antibody, PTRG_07106 antibody, LOC100283498 antibody, Cops2 antibody, csn-2 antibody, FUS12 antibody
    背景

    Synonyms: ALIEN, Alien homolog, COP 9, COP9, COP9 constitutive photomorphogenic homolog subunit 2, COP9 signalosome complex subunit 2, COPS 2, Cops2, CSN2, CSN2_HUMAN, JAB1 containing signalosome subunit 2, JAB1-containing signalosome subunit 2, SGN 2, SGN2, Signalosome subunit 2, Thyroid Hormone Receptor Interactor15, Thyroid Hormone Receptor Interactor 15, Thyroid receptor-interacting protein 15, TR-interacting protein 15, TRIP 15, TRIP-15.

    Background: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.

    基因ID
    1447
    途径
    Cell Division Cycle
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