CaM I (pSer102) 抗体
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北京 101111
Quick Overview for CaM I (pSer102) 抗体 (ABIN1386244)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer102
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated syntheticphosphopeptide derived from human CaM I around the phosphorylation site of Ser 102
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CaM I
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背景
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Synonyms: p-CaM I Ser 102, CALM 1, CALM 2, CALM 3, CALM, CALM1, CALM2, CALM3, CALML2, Calmodulin 1, Calmodulin1, CAM 1, CAM 2, CAM 3, CaM, CAM I, CAM1, CAM2, CAM3, CAMB, CAMC, CAMI, CAMIII, DD132, PHKD, Phosphorylase kinase delta, Phosphorylase kinase delta subunit, Calmodulin1, Calmodulin 1, Calmodulin-1, Calmodulin2, Calmodulin 2, Calmodulin-2, Calmodulin3, Calmodulin 3, Calmodulin-3.
Background: Calmodulin consists of two glycoproteins, 34 and 39 kDa, sometimes designated epithelial antigen, epithelial specific antigen, and epithelial glycoprotein. The glycoproteins are located on the cell membrane surface and in the cytoplasm of virtually all epithelial cells with the exception of most squamous epithelia, hepatocytes, renal proximal tubular cells, gastric parietal cells and myoepithelial cells. Epithelial Calmodulin is found in the large majority of adenocarcinomas of most sites (50-100 % in various studies, as well as neuroendocrine tumours, including small cell carcinoma. Renal cell carcinoma and hepatocellular carcinoma stain in about 30 % of the cases. Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin Ca(2+) complex are a number of protein kinases and phosphatases. Calmodulin has four functional calcium binding sites.
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基因ID
- 801
抗原
-
