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GABRG2 抗体 (pSer366)

This anti-GABRG2 antibody is a 兔 多克隆 antibody detecting GABRG2 in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 和 ICC. Suitable for 小鼠 和 大鼠.
产品编号 ABIN1386210
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GABRG2 抗体 (pSer366) (ABIN1386210)

抗原

See all GABRG2 抗体
GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))

适用

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小鼠, 大鼠

宿主

  • 63
  • 2
  • 1

克隆类型

  • 65
  • 1
多克隆

标记

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This GABRG2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
  • 抗原表位

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    pSer366

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Sheep,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human GABRG2 around the phosphorylation site of Ser366

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))

    别名

    GABRG2

    背景

    Synonyms: p-GABAA R_2 Ser 365, CAE 2, CAE2, ECA 2, ECA2, GABAA receptor subunit gamma 2, GABAA receptor subunit gamma-2, GABRG 2, GABRG2 antibody Gamma aminobutyric acid GABA A receptor gamma 2, Gamma aminobutyric acid A receptor gamma 2, Gamma aminobutyric acid receptor gamma 2 subunit, Gamma-aminobutyric acid receptor subunit gamma-2, Gamma-aminobutyric-acid receptor gamma-2 subunit, GBRG2_HUMAN, GEFSP 3, GEFSP3.

    Background: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system, GABA functions as the main inhibitory transmitter by increasing a Cl- (chloride) conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors, as well as a third class of receptors called GABAC. The ?subunit of GABAA receptors are important for benzodiazepine binding and modulation of GABA-mediated Cl- current. GABAA R? is a 467 amino acid mulit-pass membrane protein localized to the postsynaptic cell membrane. Present as a pentamer with other GABAA receptor chains (Alpha, Beta, Gamma, Delta and Epsilon), the GABAA ligand-gated Cl- channels selectively complex with D5DR to enable mutual inhibitory functional interactions between the two receptor systems. Defects in the gene encoding GABAA R Gamma 2 have been found to be the cause of childhood absence epilepsy type 2, familial febrile convulsions type 8, generalized epilepsy with febrile seizures plus type 3 and severe myoclonic epilepsy in infancy.

    基因ID

    2566
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