AFG3L2 抗体 (AA 531-600)
-
- 抗原 See all AFG3L2 抗体
- AFG3L2 (AFG3-Like Protein 2 (AFG3L2))
-
抗原表位
- AA 531-600
-
适用
- 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This AFG3L2 antibody is un-conjugated
-
应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Cow,Sheep,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human AFG3L2
- 亚型
- IgG
- Top Product
- Discover our top product AFG3L2 Primary Antibody
-
anti-AFG3-Like Protein 2 (AFG3L2) (AA 538-797) antibody
AFG3L2 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-AFG3-Like Protein 2 (AFG3L2) (AA 550-759) antibodyAFG3L2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AFG3-Like Protein 2 (AFG3L2) (C-Term) antibodyAFG3L2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-AFG3-Like Protein 2 (AFG3L2) (AA 1-797) antibodyAFG3L2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-AFG3-Like Protein 2 (AFG3L2) antibody (HRP)AFG3L2 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-AFG3-Like Protein 2 (AFG3L2) antibody (FITC)AFG3L2 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-AFG3-Like Protein 2 (AFG3L2) antibody (Biotin)AFG3L2 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-AFG3-Like Protein 2 (AFG3L2) (AA 1-250) antibodyAFG3L2 适用: 人 WB 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-AFG3-Like Protein 2 (AFG3L2) (AA 52-80), (N-Term) antibodyAFG3L2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33011 unconjugated
-
- 应用备注
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- AFG3L2 (AFG3-Like Protein 2 (AFG3L2))
- 别名
- SCA28/AFG3L2 (AFG3L2 产品)
- 背景
-
Synonyms: AFG3 ATPase family gene 3, yeast like 2, AFG3 ATPase family gene 3 like 2 yeast, AFG3 ATPase family gene 3 like 2, AFG3 like protein 2, ATPase family gene 3 like 2, ATPase family gene 3 yeast, FLJ25993, Paraplegin like protein, SCA28, Spinocerebellar ataxia 28, AFG32_HUMAN .
Background: AFG3L2 is a multi-pass membrane metalloprotease that contains one AAA (ATPase associated with diverse cellular activities) domain, a zinc-dependent binding motif, an RNA-binding region and an ATP/GTP binding site. Localizing to the mitochondrial membrane, AFG3L2 is ubiquitously expressed with highest expression levels in skeletal muscle and heart. AFG3L2 shares 69 % similarity with the yeast Afg3 protein and 49 % similarity with Paraplegin, a protein of mitochondria that is thought to be involved in signal transduction and chaperone-like activities. In mitochondria, AFG3L2 forms a complex with Paraplegin that is believed to regulate essential protein quality control. Mutations in the gene encoding either one of these proteins can result in hereditary spastic paraplegia, a degenerative spinal cord disorder that is characterized by muscle spasms, stiffness in the legs and, in some cases, incontinence.
- 途径
- Skeletal Muscle Fiber Development
-
