TBR1 抗体 (AA 35-130)
Quick Overview for TBR1 抗体 (AA 35-130) (ABIN1386199)
抗原
See all TBR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 35-130
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human TBR1
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亚型
- IgG
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anti-T-Box Brain Gene 1 (TBR1) (AA 1-108) antibody
TBR1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F6 unconjugated
anti-T-Box Brain Gene 1 (TBR1) (AA 1-108) antibodyTBR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) (AA 51-100) antibodyTBR1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, Pig, 豚鼠, 马, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) antibodyTBR1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) antibodyTBR1 适用: 小鼠, 大鼠 IHC, ICC 宿主: 豚鼠 Polyclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) (N-Term) antibodyTBR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) (AA 575-624) antibodyTBR1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) (N-Term) antibodyTBR1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) (AA 52-80) antibodyTBR1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- TBR1 (T-Box Brain Gene 1 (TBR1))
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别名
- TBR1
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背景
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Synonyms: A novel murine and human gene, TBR-1, encodes a putative transcription factor related to the Brachyrury T gene that is expressed only in postmitotic cells. T-brain-1 TBR-1 mRNA is largely restricted to the cerebral cortex, where, during embryogenesis, it defines dferent regions that give rise to the palecortex, limbic cortex and neocortex 1-3. TBR-1, Pax-6 and Emx-1 are expressed in the mouse and chicken pallium. The pallio-subpallial boundary lies at the interface between the TBR-1 and Dlx-2 expression domains. .
Background: A novel murine and human gene, TBR-1, encodes a putative transcription factor related to the Brachyrury (T) gene that is expressed only in postmitotic cells. T-brain-1 (TBR-1) mRNA is largely restricted to the cerebral cortex, where, during embryogenesis, it defines different regions that give rise to the palecortex, limbic cortex and neocortex (1-3). TBR-1, Pax-6 and Emx-1 are expressed in the mouse and chicken pallium. The pallio-subpallial boundary lies at the interface between the TBR-1 and Dlx-2 expression domains. Chicken genes homolgous to these mouse genes are expressed in topologically comparable patterns during development, suggesting that mouse and chicken may have similar histogenetic specification processes and field homologies (4). CASK/LIN-2, a membrane-associated guanylate kinase, is required for EGFR localization and signaling. In adult rat brain, CASK is concentrated at neuronal synapses and binds to the cell-surface proteins. CASK can interact with TBR-1, which is involved in forebrain development. CASK enters into the nucleus and binds to a specific DNA sequence (the T-element) in a complex with TBR-1. Thus, CASK acts as a coactivator of TBR-1 to induce transcription of T-element containing genes, including reelin (5).
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基因ID
- 10716
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UniProt
- Q16650
抗原
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