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Neudesin 抗体 (AA 51-140)

This anti-Neudesin antibody is a 兔 多克隆 antibody detecting Neudesin in WB, ELISA, ICC, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1386196
发货至: 中国

Quick Overview for Neudesin 抗体 (AA 51-140) (ABIN1386196)

抗原

See all Neudesin (NENF) 抗体
Neudesin (NENF)

适用

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宿主

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克隆类型

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多克隆

标记

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This Neudesin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 51-140

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Neudesin

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Neudesin (NENF)

    别名

    NENF/Neudesin

    背景

    Synonyms: Cell growth inhibiting protein 47, Cell immortalization-related protein 2, CIR2, Nenf, NENF_HUMAN, Neudesin, Neuron derived neurotrophic factor, Neuron-derived neurotrophic factor, SCIRP10, SCIRP10 related protein, Secreted protein of unknown function, Spinal cord injury related protein 10, SPUF, SPUF protein.

    Background: Neudesin is a 172 amino acid secreted protein that belongs to the cytochrome b5 family and MAPR subfamily. Neudesin possesses neurotrophic activity, which is enhanced by binding to heme, and may contribute to neuronal differentiation and neural cell proliferation. In primary cultured neurons, Neudesin has been observed to activate Akt1 and ERK 1 phosphorylation. Upregulated in immortal cells, Neudesin contains one cytochrome b5 heme-binding domain and is encoded by a gene that maps to human chromosome 1q32.3. Human chromosome 1 spans 260 million base pairs and comprises nearly 8 % of the human genome. A large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson?s disease, Gaucher disease, schizophrenia and Usher syndrome, map to chromosome 1.

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