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Aggrecan 抗体 (AA 601-700)

This anti-Aggrecan antibody is a 兔 多克隆 antibody detecting Aggrecan in ICC, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 大鼠, 小鼠 和 兔.
产品编号 ABIN1386175
发货至: 中国

Quick Overview for Aggrecan 抗体 (AA 601-700) (ABIN1386175)

抗原

See all Aggrecan (ACAN) 抗体
Aggrecan (ACAN)

适用

  • 90
  • 47
  • 33
  • 18
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
大鼠, 小鼠, 兔

宿主

  • 90
  • 25
  • 1
  • 1

克隆类型

  • 83
  • 34
多克隆

标记

  • 64
  • 15
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aggrecan antibody is un-conjugated

应用范围

  • 87
  • 56
  • 38
  • 29
  • 22
  • 13
  • 13
  • 12
  • 8
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
Immunocytochemistry (ICC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 10
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 601-700

    交叉反应

    小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from Human Aggrecan

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Aggrecan (ACAN)

    别名

    Aggrecan

    背景

    Synonyms: AGC1, CSPG1, MSK16, Cartilage-specific proteoglycan core protein, CSPCP, Aggrecan core protein, Chondroitin sulfate proteoglycan 1

    Background: The large chondroitin sulfate proteoglycan, aggrecan, is the predominant proteoglycan present in cartilage. Aggrecan is a member of the chondroitin sulphate proteoglycan family, which also includes versican/PG-M, neurocan and brevican. Aggrecan is a complex multidomain macromolecule that undergoes extensive processing and post-translational modification. Aggrecan in cartilage forms aggregates with hyaluronan and link protein, embedded in a collagen network. Aggrecan accounts for the compressive stiffness and resilience of the hyaline cartilage. Many forms of inflammatory arthritis are shown to be accompanied with aggrecan degradation and loss from the cartilage. Brevican is a brain proteoglycan of the aggrecan/versican/neurocan family. In the adult brain, the brevican core protein undergoes proteolytic cleavage and exists as a full-length form a carboxy-terminal fragment and an amino-terminal fragment.

    UniProt

    P16112

    途径

    Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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