CADPS2 抗体 (AA 435-510)
Quick Overview for CADPS2 抗体 (AA 435-510) (ABIN1386164)
抗原
See all CADPS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 435-510
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CADPS2
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亚型
- IgG
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anti-Ca++-Dependent Secretion Activator 2 (CADPS2) (N-Term) antibody
CADPS2 适用: 人, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Ca++-Dependent Secretion Activator 2 (CADPS2) (Center) antibodyCADPS2 适用: 人, 大鼠, 小鼠 WB, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))
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别名
- CADPS2
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背景
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Synonyms: Cadps2, Calcium-dependent activator protein for secretion 2, Calcium-dependent secretion activator 2, CAPS2, CAPS2_HUMAN.
Background: Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis. Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances. The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, as well as regulation of phospholipid binding. Through their regulation of neurotrophin release from granule cells, CAPS proteins help to regulate cell fate during neuronal development. CAPS-1 is thought to regulate catecholamine release from neuronal cells, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor and neurotrophin-3 from granule cells. Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism.
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途径
- Synaptic Vesicle Exocytosis
抗原
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