PPFIA1 抗体 (AA 141-190)
Quick Overview for PPFIA1 抗体 (AA 141-190) (ABIN1386160)
抗原
See all PPFIA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 141-190
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Liprin alpha 1
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- PPFIA1 (Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))
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别名
- Liprin alpha 1/PPFIA1
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背景
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Synonyms: LAR interacting protein 1, LIP 1, LIP.1, LIP1, LIPRIN, MGC26800, PPFIA 1, PPFIA1, Protein tyrosine phosphatase receptor type f polypeptide PTPRF interacting protein liprin alpha 1, Protein tyrosine phosphatase receptor type f polypeptide interacting protein alpha 1, PTPRF interacting protein alpha 1, LIPA1_HUMAN.
Background: Liprins interact with members of the leukocyte common antigen-related (LAR) family of transmembrane protein tyrosine phosphatases, which are implicated in axon guidance and mammary gland development. Liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR phosphatases. Based on sequence similarities and binding characteristics, liprins are subdivided into Alpha and Beta liprins. Both Alpha and Beta liprins homodimerize via their N-terminal, coiled-coil regions. Liprin Alpha1 is a ubiquitously expressed protein that interacts with the tumor suppressor ING4 to regulate cell migration and possibly prevent metastasis. The interaction between LAR and Liprin Alpha1 can be weakened by treatment of Liprin ? with calf intestinal phosphatase.
抗原
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