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DUOX1 抗体 (AA 1-100)

This anti-DUOX1 antibody is a 兔 多克隆 antibody detecting DUOX1 in ELISA, WB, IHC (p), ICC, IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1386159
发货至: 中国

Quick Overview for DUOX1 抗体 (AA 1-100) (ABIN1386159)

抗原

See all DUOX1 抗体
DUOX1 (Dual Oxidase 1 (DUOX1))

适用

人, 小鼠, 大鼠

宿主

  • 4
  • 2
  • 1

克隆类型

  • 7
多克隆

标记

  • 7
This DUOX1 antibody is un-conjugated

应用范围

ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 3
    • 1
    • 1
    • 1
    • 1
    AA 1-100

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human DUOX1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Wakatsuki, Furuno, Ohshima, Araki: "Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration." in: The Journal of cell biology, Vol. 211, Issue 4, pp. 881-96, (2015) (PubMed).

  • 抗原

    DUOX1 (Dual Oxidase 1 (DUOX1))

    别名

    DUOX1

    背景

    Synonyms: Dual oxidase 1, Dual oxidase 1 precursor, DUOX1, EC 1.11.1, EC 1.6.3.1, Flavoprotein NADPH oxidase, Large NOX 1, LNOX1, Long NOX 1, MGC138840, MGC138841, NADPH thyroid oxidase 1, Nicotinamide adenine dinucleotide phosphate oxidase, NOXEF1, THOX1, Thyroid oxidase 1, DUOX1_HUMAN.

    Background: Dual oxidase 1 (DUOX1), a homolog of glycoprotein p91Phox, is expressed in airway epithelium and generates reactive oxygen species (ROS). DUOX1 is a multi-pass membrane protein predominantly expressed in thyrocytes and tracheal surface epithelial cells, as well as thyroid, trachea and bronchium. DUOX1 generates hydrogen peroxide, which is crucial for thyroid peroxidase and lactoperoxidase. It is also involved in thyroid hormone synthesis and lactoperoxidase-mediated antimicrobial defense in mucosa. DUOX1, which also plays a role in mucin expression, is widely expressed in fetal tissues.

    基因ID

    53905
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