Frataxin 抗体
Quick Overview for Frataxin 抗体 (ABIN1386148)
抗原
See all Frataxin (FXN) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Frataxin
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亚型
- IgG
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anti-Frataxin (FXN) (AA 57-210) antibody
FXN 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal FXN-2124 unconjugated
anti-Frataxin (FXN) (AA 42-210) antibodyFXN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Frataxin (FXN) (AA 91-200) antibodyFXN 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3G9 unconjugated
anti-Frataxin (FXN) (AA 91-200) antibodyFXN 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-Frataxin (FXN) (AA 41-207) antibodyFXN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frataxin (FXN) (AA 36-64), (N-Term) antibodyFXN 适用: 人 WB 宿主: 兔 Polyclonal RB41914 unconjugated
anti-Frataxin (FXN) (AA 1-210) antibodyFXN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Frataxin (FXN) (AA 1-210) antibodyFXN 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Frataxin (FXN) (AA 105-154) antibodyFXN 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 犬, 豚鼠, 猴, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frataxin (FXN) (Internal Region) antibodyFXN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Frataxin (FXN)
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别名
- Frataxin
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背景
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Synonyms: X25, CyaY, d-FXN, FA antibody FARR, Frataxin mature form, Frataxin81-210, FRDA, FRDA_HUMAN, Friedreich ataxia protein, FXN, i-FXN, m56-FXN, m78-FXN, m81-FXN, MGC57199, MSF01, MSF31, MSF42.
Background: Friedreich ataxia is a progressive neurodegenerative disorder caused by loss of function mutations in the frataxin gene. The human frataxin gene maps to chromosome 9q13.The frataxin gene encodes a mitochondrial protein of the same name. Frataxin assembles into a stable homopolymer with iron-binding capabilities. When expressed in E. Coli human frataxin binds iron atoms at a rate of 10 iron atoms per 1 Molecule of the frataxin polymer. Thus, frataxin appears to function in some capacity for iron-storage for the mitochondria. Frataxin may also function as an activator of oxidative phosphorylation to increase mitochondrial membrane potential and elevate cellular ATP. Frataxin is expressed in tissues with high metabolic activity including heart, liver and brown fat.
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途径
- Transition Metal Ion Homeostasis, Regulation of Cell Size
抗原
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