CACNA2D1 抗体 (AA 571-610)
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- 抗原 See all CACNA2D1 抗体
- CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))
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抗原表位
- AA 571-610
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CACNA2D1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Dog,Cow,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CACNA2/CACNA2D1
- 亚型
- IgG
- Top Product
- Discover our top product CACNA2D1 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility." in: Nature communications, Vol. 8, Issue 1, pp. 1755, (2018) (PubMed).
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Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility." in: Nature communications, Vol. 8, Issue 1, pp. 1755, (2018) (PubMed).
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- 抗原
- CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))
- 别名
- CACNA2/CACNA2D1 (CACNA2D1 产品)
- 别名
- CACNA2D1 antibody, DKFZp469K2211 antibody, CACNA2 antibody, CACNL2A antibody, CCHL2A antibody, Ca(v)alpha2delta1 antibody, Cacna2 antibody, Cchl2a antibody, CCHLA2 antibody, DHSCCA antibody, calcium voltage-gated channel auxiliary subunit alpha2delta 1 antibody, calcium channel, voltage-dependent, alpha 2/delta subunit 1 antibody, calcium channel, voltage-dependent, alpha2/delta subunit 1 antibody, CACNA2D1 antibody, cacna2d1 antibody, Cacna2d1 antibody
- 背景
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Synonyms: Calcium channel L type DHPR alpha 2 subunit, CA2D1_HUMAN, CACN A2, CACNA2, CACNA2D1, CACNL2A, Calcium channel L type alpha 2 polypeptide, Calcium channel voltage dependent alpha 2/delta subunit 1, CCHL2A, Dihydropyridine receptor alpha 2 subunit, Dihydropyridine sensitive L type calcium channel alpha 2/delta subunit, Dihydropyridine sensitive L type calcium channel subunits alpha 2/delta, H_DJ0560O14.1, L type calcium channel subunit alpha 2, MHS 3, MHS3, Voltage dependent calcium channel subunit alpha 2/delta 1, Voltage gated calcium channel subunit alpha 2/delta 1, Voltage-dependent calcium channel subunit delta-1, Voltage-gated calcium channel subunit alpha-2/delta-1, WUGSC:H_DJ0560O14.1.
Background: Voltage-dependent calcium channels are essential for the release of neurotransmitters. Cacna2d1 (calcium channel, voltage-dependent, alpha 2/delta subunit 1), also known as CACNA2, CCHL2A, MHS3 or CACNL2A, is a 1,091 amino acid single-pass type I membrane protein that contains one VWFA domain and one cache domain. Expressed in skeletal muscle, aorta tissues and in the central nervous system (CNS), Cacna2d1 functions as an alpha-2/delta subunit of voltage-dependent calcium channels and plays an important role in calcium current density, as well as in excitation-contraction coupling. The Cacna2d1 precursor is proteolytically processed to produce two functional subunits, designated alpha-2-1 and delta-1, which are disulfide-linked to one another.
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