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CACNA2D1 抗体 (AA 571-610)

CACNA2D1 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386090
发货至: 中国
  • 抗原 See all CACNA2D1 抗体
    CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))
    抗原表位
    • 12
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 571-610
    适用
    • 42
    • 15
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 43
    • 1
    克隆类型
    • 44
    多克隆
    标记
    • 20
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CACNA2D1 antibody is un-conjugated
    应用范围
    • 28
    • 26
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CACNA2/CACNA2D1
    亚型
    IgG
    Top Product
    Discover our top product CACNA2D1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Chintalapudi, Maria, Di Wang, Bailey, Hysi, Wiggs, Williams, Jablonski: "Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility." in: Nature communications, Vol. 8, Issue 1, pp. 1755, (2018) (PubMed).

  • 抗原
    CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))
    别名
    CACNA2/CACNA2D1 (CACNA2D1 产品)
    别名
    CACNA2D1 antibody, DKFZp469K2211 antibody, CACNA2 antibody, CACNL2A antibody, CCHL2A antibody, Ca(v)alpha2delta1 antibody, Cacna2 antibody, Cchl2a antibody, CCHLA2 antibody, DHSCCA antibody, calcium voltage-gated channel auxiliary subunit alpha2delta 1 antibody, calcium channel, voltage-dependent, alpha 2/delta subunit 1 antibody, calcium channel, voltage-dependent, alpha2/delta subunit 1 antibody, CACNA2D1 antibody, cacna2d1 antibody, Cacna2d1 antibody
    背景

    Synonyms: Calcium channel L type DHPR alpha 2 subunit, CA2D1_HUMAN, CACN A2, CACNA2, CACNA2D1, CACNL2A, Calcium channel L type alpha 2 polypeptide, Calcium channel voltage dependent alpha 2/delta subunit 1, CCHL2A, Dihydropyridine receptor alpha 2 subunit, Dihydropyridine sensitive L type calcium channel alpha 2/delta subunit, Dihydropyridine sensitive L type calcium channel subunits alpha 2/delta, H_DJ0560O14.1, L type calcium channel subunit alpha 2, MHS 3, MHS3, Voltage dependent calcium channel subunit alpha 2/delta 1, Voltage gated calcium channel subunit alpha 2/delta 1, Voltage-dependent calcium channel subunit delta-1, Voltage-gated calcium channel subunit alpha-2/delta-1, WUGSC:H_DJ0560O14.1.

    Background: Voltage-dependent calcium channels are essential for the release of neurotransmitters. Cacna2d1 (calcium channel, voltage-dependent, alpha 2/delta subunit 1), also known as CACNA2, CCHL2A, MHS3 or CACNL2A, is a 1,091 amino acid single-pass type I membrane protein that contains one VWFA domain and one cache domain. Expressed in skeletal muscle, aorta tissues and in the central nervous system (CNS), Cacna2d1 functions as an alpha-2/delta subunit of voltage-dependent calcium channels and plays an important role in calcium current density, as well as in excitation-contraction coupling. The Cacna2d1 precursor is proteolytically processed to produce two functional subunits, designated alpha-2-1 and delta-1, which are disulfide-linked to one another.

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