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SIP1 抗体

GEMIN2 适用: 人, 小鼠, 大鼠 IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386035
发货至: 中国
  • 抗原 See all SIP1 (GEMIN2) 抗体
    SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
    适用
    • 37
    • 24
    • 23
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 33
    • 5
    克隆类型
    • 34
    • 4
    多克隆
    标记
    • 21
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIP1 antibody is un-conjugated
    应用范围
    • 19
    • 13
    • 10
    • 9
    • 6
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SIP1
    亚型
    IgG
    Top Product
    Discover our top product GEMIN2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
    别名
    SIP1 (GEMIN2 产品)
    别名
    SIP1 antibody, SIP1-delta antibody, 1700012N19Rik antibody, Sip1 antibody, sip1 antibody, sip1-delta antibody, wu:fc52a05 antibody, zgc:110274 antibody, gem nuclear organelle associated protein 2 antibody, gem (nuclear organelle) associated protein 2 antibody, gem nuclear organelle associated protein 2 S homeolog antibody, GEMIN2 antibody, Gemin2 antibody, gemin2.S antibody, gemin2 antibody
    背景

    Synonyms: Smad Interacting Protein 1 SIP 1, SIP1 SIP-1, Smad-interacting protein 1, SMADIP 1, SMADIP1, ZEB 2, ZEB2, ZEB2_HUMAN, Zfhx1b, ZFHX1B protein, Zfx1b, Zinc finger E box binding protein 2, Zinc finger E-box-binding homeobox 2, Zinc finger homeobox 1b, zinc finger homeobox protein 1, Zinc finger homeobox protein 1b.

    Background: SMAD regulates gene expression by interacting with different classes of transcription factors including DNA-binding multi-zinc finger proteins. SIP1, for SMAD interacting protein 1, is a member of the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins. SIP1 contains a SMAD-binding domain, a homeodomain and two clusters of zinc fingers on the N- and C-termini. SIP1, also known as SMADIP1, ZFHX1B and ZEB2 (zinc finger E-box-binding protein 2), can be induced by TGF treatment. SIP1 plays a crucial role in normal embryonic development of neural structures and the neural crest. The human SIP1 gene maps to chromosome 2q22. Mutations in the SIP1 gene cause a form of Hirschsprung disease (HSCR). Patients with SIP1 mutations show mental retardation, delayed motor development, epilepsy, microcephaly, distinct facial features and/or congenital heart diseaseall symptoms of HSCR.

    基因ID
    9839
    途径
    Ribonucleoprotein Complex Subunit Organization, Tube Formation
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