RSAD2 抗体
Quick Overview for RSAD2 抗体 (ABIN1386031)
抗原
See all RSAD2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Viperin/RSAD2
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亚型
- IgG
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anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 42-361) antibody
RSAD2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 262-361) antibodyRSAD2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D10 unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (C-Term) antibodyRSAD2 适用: 人, 小鼠, 犬, Cow, 兔, Pig, 斑马鱼, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) antibodyRSAD2 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 42-361) antibodyRSAD2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (C-Term) antibodyRSAD2 适用: 人, 小鼠, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (N-Term) antibodyRSAD2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) antibodyRSAD2 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 1-361) antibodyRSAD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2) (AA 101-150) antibodyRSAD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, Pig, 小鸡, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
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别名
- Viperin
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背景
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Synonyms: endoplasmic reticulum-associated, interferon-inducible, cig 33, CIG 5, cig-33, CIG-5, CIG33, CIG5, Cytomegalovirus induced gene 5 protein, Cytomegalovirus-induced gene 5 protein, Radical S-adenosyl methionine domain-containing protein 2, RSAD 2, Rsad2, RSAD2_HUMAN, RSDA-2, VIG 1, vig1, Viperin, Virus inhibitory protein, virus inhibitory protein endoplasmic reticulum associated interferon inducible.
Background: RSAD2 is a 361 amino acid protein that is involved in antiviral defense against pathogens such as Hep C, Cytomegalovirus and HIV-1. Localized to the cytosolic side of the endoplasmic reticulum and relocated to the Golgi apparatus upon viral infection, RSAD2 is thought to prevent viral budding by disrupting lipid rafts at the plasma membrane and supporting the Interferon-induced antiviral state of the cell. Additionally, RSAD2 can bind to and inactivate FDPS (an enzyme that is crucial for the synthesis of cholesterol and geranylated and farnesylated proteins), thereby playing a role in lipid synthesis. Overexpression of RSAD2 leads to abnormal lipid accumulation that is associated with atherosclerosis, a chronic inflammatory disease characterized by hardened arteries.
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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