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Receptor Accessory Protein 1 抗体 (AA 53-150)

REEP1 适用: 小鼠 WB, ELISA, IF (p), IF (cc), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386005
发货至: 中国
  • 抗原 See all Receptor Accessory Protein 1 (REEP1) 抗体
    Receptor Accessory Protein 1 (REEP1)
    抗原表位
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 53-150
    适用
    • 24
    • 11
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 25
    克隆类型
    • 25
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Receptor Accessory Protein 1 antibody is un-conjugated
    应用范围
    • 24
    • 12
    • 12
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human REEP1
    亚型
    IgG
    Top Product
    Discover our top product REEP1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    Receptor Accessory Protein 1 (REEP1)
    别名
    REEP1 (REEP1 产品)
    别名
    C2orf23 antibody, HMN5B antibody, SPG31 antibody, D6Ertd253e antibody, RGD1305230 antibody, receptor accessory protein 1 antibody, REEP1 antibody, Reep1 antibody
    背景

    Synonyms: C2orf23, Chromosome 2 open reading frame 23, FLJ13110, Receptor accessory protein 1, Receptor expression-enhancing protein 1, Reep1, REEP1_HUMAN, SPG31.

    Background: Transport of G protein-coupled receptors (GPCRs) to the cell surface membrane is critical for receptor-ligand recognition. Mammalian GPCR odorant receptors (ORs), when heterologously expressed in cells, are poorly expressed on the cell surface. REEP1 (receptor expression-enhancing protein 1), is a 201 amino acid multi-pass mitochondrion membrane protein that belongs to the DP1 family. REEP1 interacts with odorant receptor proteins and may enhance the cell surface expression of odorant receptors. Mutations in the REEP1 gene are the third most common cause of hereditary spastic paraplegia (HSP) after spastin and atlastin gene mutations. Mutations in the REEP1 gene also cause spastic paraplegia autosomal dominant type 31, a neurodegenerative disorder. The REEP1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana and rice, and maps to human chromosome 2p11.2.

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