APBB3 抗体 (AA 401-486)
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- 抗原 See all APBB3 抗体
- APBB3 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 3 (APBB3))
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抗原表位
- AA 401-486
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适用
- 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APBB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Cow,Sheep
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human APBB3/FE65L2
- 亚型
- IgG
- Top Product
- Discover our top product APBB3 Primary Antibody
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anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 3 (APBB3) (AA 1-486) antibody
APBB3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 3 (APBB3) (AA 14-302) antibodyAPBB3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 3 (APBB3) (AA 107-156) antibodyAPBB3 适用: 人, 大鼠, 小鼠, 兔, 豚鼠, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 3 (APBB3) (Center) antibodyAPBB3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 3 (APBB3) (AA 187-214) antibodyAPBB3 适用: 人 WB 宿主: 兔 Polyclonal RB43979 unconjugated
anti-Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 3 (APBB3) (N-Term) antibodyAPBB3 适用: 人, 大鼠, 小鼠, 兔, 豚鼠, Cow, 犬, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- APBB3 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 3 (APBB3))
- 别名
- APBB3/FE65L2 (APBB3 产品)
- 别名
- Fe65l2 antibody, Rirl2 antibody, TR2S antibody, MGC142933 antibody, FE65L2 antibody, SRA antibody, amyloid beta (A4) precursor protein-binding, family B, member 3 antibody, steroid receptor RNA activator 1 antibody, amyloid beta precursor protein binding family B member 3 antibody, Apbb3 antibody, SRA1 antibody, APBB3 antibody, apbb3 antibody
- 背景
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Synonyms: Amyloid beta A4 precursor protein binding family B member 3, Amyloid beta A4 precursor protein-binding family B member 3, amyloid beta precursor protein binding family B member 3, amyloid precursor interacting protein, Apbb3, APBB3_HUMAN, Fe65 like protein 2, FE65L2, Protein Fe65-like 2, SRA.
Background: Fe65L2 is a 486 amino acid protein that contains one WW domain and two PID domains. Binding to the intracellular domain of the -Amyloid precursor protein, Fe65L2 is thought to modulate the internalization and, therefore, the accessibility and function of -Amyloid. Via its ability to control the intracellular accumulation of -Amyloid, Fe65L2 is thought to play a role in the pathogenesis of Alzheimer's disease. Fe65L2 exists as four alternatively spliced isoforms designated isoform I, isoform II, isoform III and isoform IV. Fe65L2 interacts with Amyloid-like protein and is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
- 基因ID
- 10307
- UniProt
- O95704
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