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PJA2 抗体 (AA 420-470)

This anti-PJA2 antibody (ABIN1385983) is a Rabbit Polyclonal antibody detecting PJA2 in WB, IF (p), IHC (p). Suitable for Human, Mouse, Rat.
产品编号 ABIN1385983
发货至: 中国

Quick Overview for PJA2 抗体 (AA 420-470) (ABIN1385983)

抗原

See all PJA2 抗体
PJA2 (Praja Ring Finger 2 (PJA2))

适用

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人, 小鼠, 大鼠

宿主

  • 42
  • 2

克隆类型

  • 43
  • 1
多克隆

标记

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This PJA2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 14
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    • 1
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    • 1
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    AA 420-470

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PJA2/RNF131

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    PJA2 (Praja Ring Finger 2 (PJA2))

    别名

    RNF131

    背景

    Synonyms: E3 ubiquitin protein ligase Praja2, E3 ubiquitin-protein ligase Praja-2, KIAA0438, Neurodap 1, Neurodap1, PJA 2, PJA2, PJA2_HUMAN, Praja 2, Praja 2 RING H2 mot containing, praja ring finger 2, Praja ring finger 2 E3 ubiquitin protein ligase, Praja2, RING finger protein 131, RNF 131, RNF131.

    Background: PJA2, also known as E3 ubiquitin-protein ligase praja-2, RNF131 (ring finger protein 131) or Neurodap1, is a 708 amino acid protein that contains one ring-type zinc finger and exists as two alternatively spliced isoforms. Significantly conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, PJA2 shares 52 % identity with PJA1, which is involved in protein ubiquitination in brain and may play a role in X-linked mental retardation. Encoded by a gene that maps to human chromosome 5q21.3, PJA2 localizes to both endoplasmic reticulum and Golgi apparatus membranes. Participating in E2-dependent, E3 ubiquitin-protein ligase activity, PJA2 binds to a variety of E2s and interacts with ubiquitin-conjugating enzymes, such as UBE2D2, in vitro.

    基因ID

    9867

    UniProt

    O43164
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