DPH2 抗体 (AA 401-489)
Quick Overview for DPH2 抗体 (AA 401-489) (ABIN1385915)
抗原
See all DPH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 401-489
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DPH2
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- DPH2 (Diphthamide Biosynthesis Protein 2 (DPH2))
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别名
- Dph2
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背景
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Synonyms: Diphthamide biosynthesis like protein 2, Diphthamide biosynthesis protein 2, Diphthamide biosynthesis protein 2 homolog like 2, Diphthamide biosynthesis protein 2 homolog-like 2, Diptheria toxin resistance protein required for diphthamide biosynthesis like 2, Diptheria toxin resistance protein required for diphthamide biosynthesis like 2 S. cerevisiae , DPH 2, DPH2, DPH2 homolog, DPH2 homolog S. cerevisiae, DPH2 like 2, DPH2 like 2 S. cerevisiae, DPH2-like 2, DPH2_HUMAN, DPH2L2, HsDph2, OTTHUMP00000010007, Protein DPH2 homolog.
Background: DPH2 (diphthamide biosynthesis protein 2), also known as DPH2L2, is a 489 amino acid protein that shows strong expression in skeletal muscle, moderate expression in heart, small intestine, liver, pancreas, testis and colon, and lesser expression in brain, placenta, kidney, spleen, thymus, prostate, ovary and lymphocytes. DPH2 interacts with DPH1 and, functioning together as a dimer or multimer, DPH1 and DPH2 may participate in diphthamide biosynthesis. Diphthamide is a posttranslationally modified histidine residue which occurs in EF-2 (elongation factor 2) and targets diphtheria toxin ADP-ribosylation. The loss of DPH2 in Saccharomyces cerevisiae is believed to suppress zymocicity. Two transcript variants encoding different isoforms have been found for this gene.Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.Tissue specificity:Strongly expressed in skeletal muscle. Moderately expressed in heart, small intestine, liver, pancreas, testis and colon. Weakly expressed in brain, placenta, kidney, speen, thymus, prostate, ovary and lymphocytes.
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基因ID
- 1802
抗原
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