CHN1 抗体 (AA 151-250)
-
- 抗原 See all CHN1 (ARHGAP2) 抗体
- CHN1 (ARHGAP2) (rho GTPase Activating Protein 2 (ARHGAP2))
-
抗原表位
- AA 151-250
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CHN1 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Alpha-chimerin
- 亚型
- IgG
- Top Product
- Discover our top product ARHGAP2 Primary Antibody
-
anti-rho GTPase Activating Protein 2 (ARHGAP2) (AA 91-200) antibody
ARHGAP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) antibodyARHGAP2 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) antibodyARHGAP2 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) antibodyARHGAP2 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3C6 unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) antibodyARHGAP2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) (AA 1-200) antibodyARHGAP2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) (AA 91-200) antibodyARHGAP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) (AA 1-459) antibodyARHGAP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) (AA 1-459) antibodyARHGAP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- CHN1 (ARHGAP2) (rho GTPase Activating Protein 2 (ARHGAP2))
- 别名
- CHN 1/Alpha-chimerin (ARHGAP2 产品)
- 别名
- ARHGAP2 antibody, CHN antibody, DURS2 antibody, NC antibody, RHOGAP2 antibody, 0610007I19Rik antibody, 0710001E19Rik antibody, 1700112L09Rik antibody, 2900046J01Rik antibody, AI413815 antibody, chimaerin antibody, wu:fr89a09 antibody, zgc:56160 antibody, zgc:92906 antibody, N-chimaerin antibody, chimerin 1 antibody, chimerin 1 L homeolog antibody, CHN1 antibody, Chn1 antibody, chn1.L antibody, chn1 antibody
- 背景
-
Synonyms: A-chimaerin, Alpha-chimerin, ARHGAP2, CHIN_HUMAN, CHN, Chn1, N chimaerin, N chimerin, N-chimaerin, N-chimerin, NC, Rho GTPase-activating protein 2, RHOGAP2.
Background: The Rac-GAP chimaerin family member Alpha-chimaerin (also known as N-chimaerin or rho GTPase-activating protein 2) has two splice variants: Alpha1 and Alpha2. The ?-chimaerin variant is a neuron-specific, diacylglycerol-binding and GTPase-activating protein for ras-related protein Rac 1. This variant lacks the N-terminal SH2 domain that is present in the Alpha2 variant. By inactivating Rac 1, Alpha1-chimaerin plays a significant role in the regulation of dendritic growth during neuronal development. It is recruited to the plasma membrane by phospholipase C Beta-coupled cell surface receptors activating the downstream generation of DAG (diacylglycerol). Overexpression of Alpha1-chimaerin results in dendritic spine retraction and the loss of dendritic branches. In the presence of reduced neuronal activity, Alpha1-chimaerin expression is down-regulated resulting in an increase in spine growth and dendritic branching.
-
