CHN1 抗体 (AA 151-250)
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北京 101111
Quick Overview for CHN1 抗体 (AA 151-250) (ABIN1385870)
抗原
See all CHN1 (ARHGAP2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-250
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Alpha-chimerin
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亚型
- IgG
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anti-rho GTPase Activating Protein 2 (ARHGAP2) (AA 91-200) antibody
ARHGAP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) antibodyARHGAP2 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) antibodyARHGAP2 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) antibodyARHGAP2 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3C6 unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) (AA 1-200) antibodyARHGAP2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) (AA 91-200) antibodyARHGAP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) (AA 264-313) antibodyARHGAP2 适用: 人, 小鼠, 大鼠, 犬, 马, 斑马鱼, 豚鼠, 猴, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) (AA 1-459) antibodyARHGAP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) (AA 1-459) antibodyARHGAP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-rho GTPase Activating Protein 2 (ARHGAP2) (AA 229-278) antibodyARHGAP2 适用: 人, 小鼠, 大鼠, 犬, 马, 斑马鱼, Cow, 兔, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CHN1 (ARHGAP2) (rho GTPase Activating Protein 2 (ARHGAP2))
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别名
- CHN 1/Alpha-chimerin
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背景
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Synonyms: A-chimaerin, Alpha-chimerin, ARHGAP2, CHIN_HUMAN, CHN, Chn1, N chimaerin, N chimerin, N-chimaerin, N-chimerin, NC, Rho GTPase-activating protein 2, RHOGAP2.
Background: The Rac-GAP chimaerin family member Alpha-chimaerin (also known as N-chimaerin or rho GTPase-activating protein 2) has two splice variants: Alpha1 and Alpha2. The ?-chimaerin variant is a neuron-specific, diacylglycerol-binding and GTPase-activating protein for ras-related protein Rac 1. This variant lacks the N-terminal SH2 domain that is present in the Alpha2 variant. By inactivating Rac 1, Alpha1-chimaerin plays a significant role in the regulation of dendritic growth during neuronal development. It is recruited to the plasma membrane by phospholipase C Beta-coupled cell surface receptors activating the downstream generation of DAG (diacylglycerol). Overexpression of Alpha1-chimaerin results in dendritic spine retraction and the loss of dendritic branches. In the presence of reduced neuronal activity, Alpha1-chimaerin expression is down-regulated resulting in an increase in spine growth and dendritic branching.
抗原
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