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ELL 抗体 (AA 531-620)

This anti-ELL antibody is a 兔 多克隆 antibody detecting ELL in ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1385855
发货至: 中国

Quick Overview for ELL 抗体 (AA 531-620) (ABIN1385855)

抗原

See all ELL 抗体
ELL (Elongation Factor RNA Polymerase II (ELL))

适用

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宿主

  • 48
  • 2

克隆类型

  • 50
多克隆

标记

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This ELL antibody is un-conjugated

应用范围

  • 25
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  • 2
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  • 1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 8
    • 4
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    • 2
    • 1
    • 1
    • 1
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    • 1
    AA 531-620

    预测反应

    Human,Mouse,Rat,Dog,Cow,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ELL

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    ELL (Elongation Factor RNA Polymerase II (ELL))

    别名

    ELL

    背景

    Synonyms: ELL_HUMAN, Eleven nineteen lysine rich leukemia gene, Eleven-nineteen lysine-rich leukemia protein, ELL1, elongation factor RNA polymerase II, Men, RNA polymerase II elongation factor, RNA polymerase II elongation factor ELL.

    Background: Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. The gene encoding human ELL, which maps to chromosome 19p13.1, is one of several genes that undergo translocation with the MLL gene on chromosome 11q23 in acute myeloid leukemia. MLL (myeloid/lymphoid leukemia, also designated ALL-1 and HRX) regulates embryonal and hematopoietic development.

    基因ID

    8178
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