Znf423 抗体 (AA 901-1000)
Quick Overview for Znf423 抗体 (AA 901-1000) (ABIN1385826)
抗原
See all Znf423 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 901-1000
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特异性
- This antibody may also detect the protein Midasin if used in Human.
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Chicken,Zebrafish
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ZNF423/OAZ
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Znf423 (Zinc Finger Protein 423 (Znf423))
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别名
- ZNF423/OAZ
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背景
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Synonyms: OAZ, Roaz, hOAZ, Ebfaz, JBTS19, NPHP14, ZFP423, Zfp104, Zinc finger protein 423, Olf1/EBF-associated zinc finger protein, Smad- and Olf-interacting zinc finger protein, ZNF423, KIAA0760
Background: Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation, this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.
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基因ID
- 23090
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UniProt
- Q2M1K9
抗原
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