ATAD3A 抗体
Quick Overview for ATAD3A 抗体 (ABIN1385769)
抗原
See all ATAD3A 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ATAD3A
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ATAD3A (ATPase Family, AAA Domain Containing 3A (ATAD3A))
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别名
- ATAD3A
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背景
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Synonyms: AAA-ATPase TOB3, ATAD3B, ATAD3C, Atad3a, ATPase family AAA domain containing protein 3A, ATPase family AAA domain-containing protein 3, ATPase family, AAA domain containing 3A, FLJ10709, FLJ35514, AAA ATPase TOB3, AAA-TOB3, ATPase family AAA domain containing protein 3B, ATPase family, AAA domain containing 3B, ATPase family, AAA domain containing, member 3B, TOB3, ATD3A_HUMAN, ATAD3A/B/C.
Background: The AAA ATPase family of molecular chaperones are characterized by a highly conserved AAA motif. Composed of 200-250 residues, the AAA domain contains Walker homology sequences and imparts ATPase activity. Members of the AAA ATPase family act as DNA helicases as well as transcription factors and are thought to be involved in several cellular functions such as cell-cycle regulation, protein proteolysis, organelle biogenesis and vesicle-mediated protein transport. Mitochondrial membrane proteins ATAD3A and ATAD3B contribute to the stabilization of nucleoids which are large mitochondrial DNA (mtDNA)-protein complexes. ATAD3A/B may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The genes encoding ATAD3A/B/C maps to human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome.
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基因ID
- 55210
抗原
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