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EBF2 抗体 (AA 331-400)

EBF2 适用: 人 ELISA, IF (p), IF (cc), ICC, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1385751
发货至: 中国
  • 抗原 See all EBF2 抗体
    EBF2 (Early B-Cell Factor 2 (EBF2))
    抗原表位
    • 14
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 331-400
    适用
    • 36
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    宿主
    • 35
    • 2
    克隆类型
    • 37
    多克隆
    标记
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EBF2 antibody is un-conjugated
    应用范围
    • 12
    • 12
    • 12
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human EBF2
    亚型
    IgG
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Bradshaw, Trossbach, Köber, Walter, Prikulis, Weggen, Korth: "Disrupted in Schizophrenia 1 regulates the processing of reelin in the perinatal cortex." in: Schizophrenia research, Vol. 215, pp. 506-513, (2021) (PubMed).

  • 抗原
    EBF2 (Early B-Cell Factor 2 (EBF2))
    别名
    EBF2 (EBF2 产品)
    别名
    EBF2 antibody, Zcoe2 antibody, D14Ggc1e antibody, EBF-2 antibody, Mmot1 antibody, O/E-3 antibody, OE-3 antibody, EBF-2-A antibody, Xcoe-2 antibody, Xcoe2 antibody, Xebf-2 antibody, Xebf-2-A antibody, Xebf2 antibody, coe2 antibody, coe2-a antibody, ebf2 antibody, oe3 antibody, COE2 antibody, early B-cell factor 2 antibody, early B cell factor 2 antibody, early B-cell factor 2 S homeolog antibody, EBF2 antibody, ebf2 antibody, Ebf2 antibody, ebf2.S antibody
    背景

    Synonyms: COE 2, COE2, Collier Olf and EBF 2, Early B cell factor 2, EBF 2, FLJ11500, Metencephalon mesencephalnon olfactory transcription factor 1, O/E 3, O/E3, OE 3, OE3, OLF 1/EBF like 3, Transcription factor COE2, COE2_HUMAN.

    Background: Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. Localized to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.

    基因ID
    64641
    UniProt
    Q9HAK2
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