EBF2 抗体 (AA 331-400)
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- 抗原 See all EBF2 抗体
- EBF2 (Early B-Cell Factor 2 (EBF2))
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抗原表位
- AA 331-400
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EBF2 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human EBF2
- 亚型
- IgG
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Disrupted in Schizophrenia 1 regulates the processing of reelin in the perinatal cortex." in: Schizophrenia research, Vol. 215, pp. 506-513, (2021) (PubMed).
: "
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Disrupted in Schizophrenia 1 regulates the processing of reelin in the perinatal cortex." in: Schizophrenia research, Vol. 215, pp. 506-513, (2021) (PubMed).
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- 抗原
- EBF2 (Early B-Cell Factor 2 (EBF2))
- 别名
- EBF2 (EBF2 产品)
- 别名
- EBF2 antibody, Zcoe2 antibody, D14Ggc1e antibody, EBF-2 antibody, Mmot1 antibody, O/E-3 antibody, OE-3 antibody, EBF-2-A antibody, Xcoe-2 antibody, Xcoe2 antibody, Xebf-2 antibody, Xebf-2-A antibody, Xebf2 antibody, coe2 antibody, coe2-a antibody, ebf2 antibody, oe3 antibody, COE2 antibody, early B-cell factor 2 antibody, early B cell factor 2 antibody, early B-cell factor 2 S homeolog antibody, EBF2 antibody, ebf2 antibody, Ebf2 antibody, ebf2.S antibody
- 背景
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Synonyms: COE 2, COE2, Collier Olf and EBF 2, Early B cell factor 2, EBF 2, FLJ11500, Metencephalon mesencephalnon olfactory transcription factor 1, O/E 3, O/E3, OE 3, OE3, OLF 1/EBF like 3, Transcription factor COE2, COE2_HUMAN.
Background: Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. Localized to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.
- 基因ID
- 64641
- UniProt
- Q9HAK2
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