EBF2 抗体 (AA 331-400)
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北京 101111
Quick Overview for EBF2 抗体 (AA 331-400) (ABIN1385751)
抗原
See all EBF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-400
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human EBF2
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亚型
- IgG
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anti-Early B-Cell Factor 2 (EBF2) (AA 53-254) antibody
EBF2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Early B-Cell Factor 2 (EBF2) antibodyEBF2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Early B-Cell Factor 2 (EBF2) (AA 405-454) antibodyEBF2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 猴, Pig, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Early B-Cell Factor 2 (EBF2) (AA 359-408) antibodyEBF2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 猴, Pig, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Early B-Cell Factor 2 (EBF2) (AA 285-536) antibodyEBF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Early B-Cell Factor 2 (EBF2) (Middle Region) antibodyEBF2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Disrupted in Schizophrenia 1 regulates the processing of reelin in the perinatal cortex." in: Schizophrenia research, Vol. 215, pp. 506-513, (2021) (PubMed).
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: "Disrupted in Schizophrenia 1 regulates the processing of reelin in the perinatal cortex." in: Schizophrenia research, Vol. 215, pp. 506-513, (2021) (PubMed).
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- EBF2 (Early B-Cell Factor 2 (EBF2))
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别名
- EBF2
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背景
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Synonyms: COE 2, COE2, Collier Olf and EBF 2, Early B cell factor 2, EBF 2, FLJ11500, Metencephalon mesencephalnon olfactory transcription factor 1, O/E 3, O/E3, OE 3, OE3, OLF 1/EBF like 3, Transcription factor COE2, COE2_HUMAN.
Background: Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. Localized to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.
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基因ID
- 64641
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UniProt
- Q9HAK2
抗原
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