UBE2L6 抗体 (AA 21-120)
Quick Overview for UBE2L6 抗体 (AA 21-120) (ABIN1385712)
抗原
See all UBE2L6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-120
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交叉反应
- 大鼠
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预测反应
- Human,Mouse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Ube2L6
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
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别名
- Ube2L6
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背景
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Synonyms: Retinoic acid induced gene B protein, Retinoic acid-induced gene B protein, RIG B, RIG-B, UB2L6_HUMAN, UBCH 8, UBCH8, UBE2L6, Ubiquitin carrier protein, Ubiquitin carrier protein L6, Ubiquitin conjugating enzyme E2L 6, Ubiquitin protein ligase, Ubiquitin protein ligase L6, Ubiquitin-protein ligase L6, Ubiquitin/ISG15 conjugating enzyme E2 L6, Ubiquitin/ISG15-conjugating enzyme E2 L6.
Background: Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells, either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign, and improperly folded proteins by targeting them for proteosome degradation. Ubiquitin conjugating enzyme 8 (UBC8) is an E2 enzyme involved in the ubiquitin pathway for protein degradation. Like other E2 enzymes, UBC8 forms a thioester bond with ubiquitin in an E1-dependent manner. UBC8 binds to the human homolog of Drosophila ariadne (HHARI) and UBC7-associated protein (H7-AP1) as well as double ring-finger protein (Dorfin). UBC8 is enriched in the central nervous system and interacts with Parkin, a RING-finger-containing protein implicated in the pathogenesis of familial Parkinson?s disease. Parkin shares sequence homology with other UBC8 binding proteins such as HHARI and H7-AP1.
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基因ID
- 9246
抗原
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