Cathelicidin 抗体
Quick Overview for Cathelicidin 抗体 (ABIN1385703)
抗原
See all Cathelicidin (CAMP) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
预测反应
- Mouse,Rat
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from mouse Calicidin
-
亚型
- IgG
-
-
anti-Cathelicidin Antimicrobial Peptide (CAMP) (AA 31-170) antibody
CAMP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) antibodyCAMP 适用: 人 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal OSX12 unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) (AA 31-172) antibodyCAMP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) (AA 31-170) antibodyCAMP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) antibodyCAMP 适用: 人 WB, IHC 宿主: 绵羊 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) antibodyCAMP 适用: 人 WB, ICC, IF 宿主: 小鼠 Monoclonal H7 unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) (AA 1-170) antibodyCAMP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) (C-Term) antibodyCAMP 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) (AA 31-170) antibodyCAMP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathelicidin Antimicrobial Peptide (CAMP) (AA 30-175) antibodyCAMP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IHC-P 1:100-500
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))
-
别名
- Cathelicidin
-
背景
-
Synonyms: 18 kDa cationic antimicrobial protein; Antibacterial protein FALL-39; Antibacterial protein LL-37; CAMP; CRAMP_MOUSE; CAP 18; CAP-18; CAP18; cathelicidin antimicrobial peptide; Cathelicidin antimicrobial peptide precursor; Cathelin-like protein; Cathelin-related antimicrobial peptide; CATHL3; Cationic antimicrobial protein CAP 18; Cationic antimicrobial protein, 18-KD; CLP; Cnlp; Cramp; CRAMP, mouse, homolog of; FALL 39; FALL 39 peptide antibiotic; FALL-39 peptide antibiotic; FALL39; hCAP 18; hCAP-18; hCAP18; HSD26; LL 37; LL37; MCLP; mcramp; Peptide antibiotic, PR-39, porcine, homolog of; SOB3.
Background: Cathelicidins are a family of antimicrobial proteins found in the peroxidase-negative granules of neutrophils. Along with the family of proteins known as defensins, cathelicidins participate in the first line of defense by preventing local infection and systemic invasion of microbes. FALL-39 precursor (FALL-39 peptide antibiotic, cationic anti-microbial protein, CAMP, CAP-18, HSD26) is a cathelicidin anti-microbial protein that contains the antibacterial peptide LL-37 (amino acids 134-170). In contrast to the defensins, which are cysteine-rich peptides that fold in -pleated sheets, LL-37 is a cysteine-free peptide that can adopt an amphipathic å-helical conformation. LL-37 binds to bacterial lipopolysaccharides (LPS) and is a potent chemotactic factor for recruiting mast cells to sites of inflammation. LL-37 is present in inflammatory skin diseases that include psoriasis, sub-acute lupus erthematosus, dermatitis and nickel contact hypersensitivity. It is not found in normal skin epidermis. The secreted protein is expressed primarily in bone marrow, testis and neutrophils. The mouse and rat ortholog, CRAMP (cathelin-related antimicrobial peptide), is also part of the cathelicidin family of host defense peptides. These include precursors of potent antimicrobial peptides that direct antimicrobial activity against various microbial pathogens and also activate mesenchymal cells during wound repair. CRAMP is expressed in testis, spleen, stomach and intestine.
-
途径
- Cellular Response to Molecule of Bacterial Origin
抗原
-
