FBXW12 抗体
Quick Overview for FBXW12 抗体 (ABIN1385341)
抗原
See all FBXW12 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FBXW12/FBXO35
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亚型
- IgG
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anti-F-Box and WD Repeat Domain Containing 12 (FBXW12) (AA 265-354) antibody
FBXW12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A9 unconjugated
anti-F-Box and WD Repeat Domain Containing 12 (FBXW12) (AA 1-250) antibodyFBXW12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 12 (FBXW12) (AA 291-320), (C-Term) antibodyFBXW12 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB27619 unconjugated
anti-F-Box and WD Repeat Domain Containing 12 (FBXW12) (AA 298-328), (C-Term) antibodyFBXW12 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- FBXW12 (F-Box and WD Repeat Domain Containing 12 (FBXW12))
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别名
- FBXW12
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背景
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Synonyms: F box and WD 40 domain containing protein 12; F box and WD 40 domain protein 12; F box and WD repeat domain containing 12; F box and WD40 repeat containing protein; F box only protein 35; F box/WD repeat containing protein 12; F-box and WD-40 domain-containing protein 12; F-box only protein 35; F-box/WD repeat-containing protein 12; Fbw12; FBW12_HUMAN; FBX12; FBXO12; FBXO35; FBXW 12; FBXW12.
Background: Belonging to the F-box family of proteins, FBXO35 (F-box only protein 35), also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), is a 464 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and -catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO35 can directly interact with Skp1 p19 and CUL-1. FBXO35 is ubiquitously expressed at low levels in most human tissues.
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基因ID
- 285231
抗原
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