LRRC59 抗体 (AA 21-120)
Quick Overview for LRRC59 抗体 (AA 21-120) (ABIN1385303)
抗原
See all LRRC59 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 21-120
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                                            交叉反应
- 小鼠, 大鼠
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                                            预测反应
- Human,Dog,Horse
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                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from human LRRC59
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                                            亚型
- IgG
 
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                                            应用备注
- 
                        WB 1:300-5000
 ELISA 1:500-1000
 IHC-P 1:200-400
 IHC-F 1:100-500
 IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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                                            有效期
- 12 months
 
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    - LRRC59 (Leucine Rich Repeat Containing 59 (LRRC59))
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                                            别名
- LRRC59
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                                            背景
- 
                        Synonyms: Leucine-rich repeat-containing protein 59, LRC59_HUMAN, LRRC59, PRO1855. Background: LRRC59 (leucine rich repeat containing 59), also known as PRO1855, is a 307 amino acid protein that contains leucine-rich repeats and may play a role in protein binding events throughout the cell. The gene encoding LRRC59 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. 
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                                            基因ID
- 55379
 抗原
- 
                    
 
                                     
                                     
                                    