RAB3GAP1 抗体 (AA 501-600)
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北京 101111
Quick Overview for RAB3GAP1 抗体 (AA 501-600) (ABIN1385218)
抗原
See all RAB3GAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-600
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预测反应
- Human,Mouse,Rat,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RAB3GAP1
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亚型
- IgG
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anti-RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1) (AA 527-653), (Catalytic Subunit) antibody
RAB3GAP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1) (Internal Region) antibodyRAB3GAP1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1) (AA 538-587) antibodyRAB3GAP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- RAB3GAP1 (RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1))
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别名
- RAB3GAP1
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背景
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Synonyms: DKFZp434A012, KIAA0066, P130, Rab3 GAP, Rab3 GAP p130, RAB3 GTPase activating protein 130 kDa subunit, Rab3 GTPase activating protein catalytic subunit, RAB3GAP, RAB3GAP130, WARBM1, RB3GP_HUMAN.
Background: Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab 3 GAP p130, also known as Rab3 GTPase-activating protein catalytic subunit, is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab 3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP, and is required for normal eye and brain development. Defects in Rab 3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1). WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab 3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters. Existing as two alternatively spliced isoforms, the Rab 3 GAP p130 gene is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish and fruit fly, and maps to human chromosome 2q21.3.
抗原
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