ZBTB17 抗体 (AA 331-430)
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北京 101111
Quick Overview for ZBTB17 抗体 (AA 331-430) (ABIN1385184)
抗原
See all ZBTB17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-430
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Miz1/ZNF60
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亚型
- IgG
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anti-Zinc Finger and BTB Domain Containing 17 (ZBTB17) (AA 121-360) antibody
ZBTB17 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 17 (ZBTB17) antibodyZBTB17 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 17 (ZBTB17) (Internal Region) antibodyZBTB17 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Increased expression of Myc-interacting zinc finger protein 1 in APP/PS1 mice." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5751-5756, (2017) (PubMed).
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: "Increased expression of Myc-interacting zinc finger protein 1 in APP/PS1 mice." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5751-5756, (2017) (PubMed).
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- ZBTB17 (Zinc Finger and BTB Domain Containing 17 (ZBTB17))
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别名
- Miz1/ZNF60
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背景
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Synonyms: Miz-1, Myc-interacting zinc finger protein 1, Myc-interacting zinc finger protein, ZBT17, ZBT17_HUMAN, Zbtb17, Zinc finger and BTB domain containing protein 17, Zinc finger and BTB domain-containing protein 17, Zinc finger protein 151, Zinc finger protein 60, ZNF151, ZNF60.
Background: The Myc family, including c-Myc-, N-Myc- and L-Myc, are nuclear proteins with relatively short half lives that contribute an important role in cellular processes such as proliferation, differentiation, apoptosis and transformation. The c-Myc protein activates transcription as part of a heteromeric complex with a number of interacting partners, including Max and Mxi 1, however the transforming properties of the Myc proto-oncogene are believed to be associated with Myc-mediated transcriptional repression. A POZ domain Zn finger protein, designated Miz-1 for Myc-interacting Zn finger protein-1, is a specific target of Myc-induced gene repression. Miz-1 interacts with Myc, but not Max or other Myc partners, and binding of Myc to Miz-1 requires the helix-loop-helix domain of Myc and a short amphipathic helix located in the carboxy-terminus of Miz-1. Miz-1 associates with DNA elements on the adenovirus major late and cyclin D1 promoters and activates transcription of both promoters. Expression of Miz-1 induces potent growth arrest function, and this latency is reversed by the addition of Myc.
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, ER-Nucleus Signaling
抗原
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