SH3TC2 抗体 (AA 851-950)
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北京 101111
Quick Overview for SH3TC2 抗体 (AA 851-950) (ABIN1385180)
抗原
See all SH3TC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 851-950
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预测反应
- Human,Mouse,Rat,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SH3TC2
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亚型
- IgG
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anti-SH3 Domain and Tetratricopeptide Repeats 2 (SH3TC2) (AA 188-427) antibody
SH3TC2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SH3 Domain and Tetratricopeptide Repeats 2 (SH3TC2) (C-Term) antibodySH3TC2 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- SH3TC2 (SH3 Domain and Tetratricopeptide Repeats 2 (SH3TC2))
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别名
- SH3TC2
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背景
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Synonyms: KIAA1985, CMT4C, D430044G18Rik, FLJ13605, MNMN, PP12494, RGD1309038, S3TC2_HUMAN, SH3 domain and tetratricopeptide repeats-containing protein 2, SH3TC2.
Background: SH3TC2 (SH3 domain and tetratricopeptide repeats 2) is a 1,288 amino acid protein that contains one SH3 domain and eight TPR repeats. The SH3TC2 gene encodes a protein expressed in Schwann cells of peripheral nerves, and localized to the plasma membrane and to the perinuclear endocytic recycling compartment, suggesting a possible function in myelination and/or in regions of axoglial interactions. The SH3TC2 protein is expressed in adult heart, testis, spinal cord, and brain as well as in fetal brain and liver. Mild mononeuropathy of the median nerve (MNMN) is caused by heterozygous mutation in the SH3TC2 gene. Also, Charcot-Marie-Tooth disease type 4C (CMT4C) is a more severe neuropathy caused by homozygous or compound heterozygous mutation in the SH3TC2 gene. Existing as four alternatively spliced isoforms and containing 18 exons, the SH3TC2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 5q32.
抗原
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