CD2 抗体
Quick Overview for CD2 抗体 (ABIN1383690)
抗原
See all CD2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognises the Lymphocyte Function associated Antigen-2 (LFA-2), a 50 kDa protein
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纯化方法
- Ion exchange chromatography
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过滤
- 0.22 μm filtered
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免疫原
- Human thymocytes,Myeloma X63/AG.8653 x Balb/c spleen cells
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亚型
- IgG2b, kappa
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Biological Activity Comment
- Inhibits mixed lymphocyte culture
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
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储存液
- Without preservative
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储存条件
- 4 °C
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储存方法
- Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
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Successful allogeneic hemopoietic stem cell transplantation in a child who had anhidrotic ectodermal dysplasia with immunodeficiency." in: Pediatrics, Vol. 118, Issue 1, pp. e205-11, (2006) (PubMed).
: "Administration of herpes simplex-thymidine kinase-expressing donor T cells with a T-cell-depleted allogeneic marrow graft." in: Blood, Vol. 97, Issue 1, pp. 63-72, (2001) (PubMed).
: "A phase II study of BTI-322, a monoclonal anti-CD2 antibody, for treatment of steroid-resistant acute graft-versus-host disease." in: Blood, Vol. 92, Issue 11, pp. 4066-71, (1999) (PubMed).
: "Treatment of familial hemophagocytic lymphohistiocytosis with bone marrow transplantation from HLA genetically nonidentical donors." in: Blood, Vol. 90, Issue 12, pp. 4743-8, (1997) (PubMed).
: "A phase II trial of partially incompatible bone marrow transplantation for high-risk acute lymphoblastic leukaemia in children: prevention of graft rejection with anti-LFA-1 and anti-CD2 antibodies. Société Française de Greffe de Moelle Osseuse." in: British journal of haematology, Vol. 93, Issue 1, pp. 131-8, (1996) (PubMed).
: "Bone marrow transplantation from genetically HLA-nonidentical donors in children with fatal inherited disorders excluding severe combined immunodeficiencies: use of two monoclonal antibodies to prevent graft rejection." in: Pediatrics, Vol. 98, Issue 3 Pt 1, pp. 420-8, (1996) (PubMed).
: "Sequential use of three monoclonal antibodies in corticosteroid-resistant acute GVHD: a multicentric pilot study including 15 patients." in: Bone marrow transplantation, Vol. 15, Issue 5, pp. 669-77, (1995) (PubMed).
: "
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Successful allogeneic hemopoietic stem cell transplantation in a child who had anhidrotic ectodermal dysplasia with immunodeficiency." in: Pediatrics, Vol. 118, Issue 1, pp. e205-11, (2006) (PubMed).
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- CD2
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别名
- CD2
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背景
- LFA-2
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分子量
- 50 kDa
抗原
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