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IL13RA2 抗体

There are 8+ publications for this product available. The 小鼠 单克隆 anti-IL13RA2 antibody is suitable to detect IL13RA2 in samples from 人. It has been validated for ELISA, IHC 和 FACS.
产品编号 ABIN1383686
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL13RA2 抗体 (ABIN1383686)

抗原

See all IL13RA2 抗体
IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL13RA2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

B-D13
  • 特异性

    Recognises the IL-13 receptor a2 (IL-13 Ra2), a 44 kDa protein

    纯化方法

    Ion exchange chromatography

    过滤

    0.22 μm filtered

    免疫原

    IL-13Ra2 transfected CHO cell line,Myeloma X63/AG.8653 x Balb/c spleen cells

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

    储存液

    Without preservative

    储存条件

    4 °C

    储存方法

    Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
  • Kawakami, Terabe, Kioi, Berzofsky, Puri: "Intratumoral therapy with IL13-PE38 results in effective CTL-mediated suppression of IL-13Ralpha2-expressing contralateral tumors." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 15, pp. 4678-86, (2006) (PubMed).

    Kawakami, Kawakami, Puri: "Specifically targeted killing of interleukin-13 (IL-13) receptor-expressing breast cancer by IL-13 fusion cytotoxin in animal model of human disease." in: Molecular cancer therapeutics, Vol. 3, Issue 2, pp. 137-47, (2004) (PubMed).

    Blanchard, Durual, Estienne, Bouzakri, Heim, Blin, Cuber: "IL-4 and IL-13 up-regulate intestinal trefoil factor expression: requirement for STAT6 and de novo protein synthesis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 6, pp. 3775-83, (2004) (PubMed).

    Kawakami, Kawakami, Kasperbauer, Hinkley, Tsukuda, Strome, Puri: "Interleukin-13 receptor alpha2 chain in human head and neck cancer serves as a unique diagnostic marker." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 9, Issue 17, pp. 6381-8, (2003) (PubMed).

    Joshi, Kawakami, Leland, Puri: "Heterogeneity in interleukin-13 receptor expression and subunit structure in squamous cell carcinoma of head and neck: differential sensitivity to chimeric fusion proteins comprised of interleukin-13 and a mutated form of Pseudomonas exotoxin." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 8, Issue 6, pp. 1948-56, (2002) (PubMed).

    Lordan, Bucchieri, Richter, Konstantinidis, Holloway, Thornber, Puddicombe, Buchanan, Wilson, Djukanović, Holgate, Davies: "Cooperative effects of Th2 cytokines and allergen on normal and asthmatic bronchial epithelial cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 1, pp. 407-14, (2002) (PubMed).

    Kawakami, Kawakami, Puri: "IL-13 receptor-targeted cytotoxin cancer therapy leads to complete eradication of tumors with the aid of phagocytic cells in nude mice model of human cancer." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 12, pp. 7119-26, (2002) (PubMed).

    Joshi, Plautz, Puri: "Interleukin-13 receptor alpha chain: a novel tumor-associated transmembrane protein in primary explants of human malignant gliomas." in: Cancer research, Vol. 60, Issue 5, pp. 1168-72, (2000) (PubMed).

  • 抗原

    IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))

    别名

    CD213a2

    背景

    IL-13Ra2

    分子量

    74 kDa
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