UBXN6 抗体
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北京 101111
Quick Overview for UBXN6 抗体 (ABIN1381743)
抗原
See all UBXN6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Detects both isoforms
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无交叉反应
- 小鼠
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纯化方法
- purified
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免疫原
- recombinant protein purified from bacteria
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亚型
- IgG1
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anti-UBX Domain Protein 6 (UBXN6) (AA 1-388) antibody
UBXN6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-UBX Domain Protein 6 (UBXN6) (AA 281-309), (C-Term) antibodyUBXN6 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB25657 unconjugated
anti-UBX Domain Protein 6 (UBXN6) (AA 301-350) antibodyUBXN6 适用: 人, 小鼠, 犬, 马, Cow, 豚鼠, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-UBX Domain Protein 6 (UBXN6) (C-Term) antibodyUBXN6 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.5 % PBS, 50 % glycerol, 0.1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C
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储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
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- UBXN6 (UBX Domain Protein 6 (UBXN6))
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别名
- UBXD1 (Full Length and Short Isoform)
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背景
- P97 is a highly abundant and conserved member of the AAA family of ATPase. It has been termed an ubiquitin selective chaperone as it functions within the ubiquitin and/or proteasome pathway. p97 does not interact with ubiquitinated substrates on its own, but requires specific adapters that interact with ubiquitinated substrates and p97 and recruits p97 to substrates. One family of adapters contains a UBX domain, which has been shown with certain adapters to function as a p97-binding module. UBXD1 is a UBX domain containing protein and p97 adapter. This adapter is unique in that it does not harbor an ubiquitin association domain and binds p97 via its PUG domain (another p97 binding motif). Two isoforms of UBXD1 are produced in cells, a full-length form of approximately 54 kDa, and an alternatively spliced variant that lacks the amino-terminal translational start site, and encodes a 47 kDa protein that is derived from an internal translational initiation site. UBXD1 expression at the RNA level has been shown to trend lower in poor prognostic cancers, including those of the breast and prostate.
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UniProt
- Q9BZV1
抗原
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