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UBXN6 抗体

UBXN6 适用: 人, 小鼠 WB, IF, IP 宿主: 小鼠 Monoclonal 2F8-24 unconjugated
产品编号 ABIN1381742
发货至: 中国
  • 抗原 See all UBXN6 抗体
    UBXN6 (UBX Domain Protein 6 (UBXN6))
    适用
    • 28
    • 14
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 27
    • 1
    小鼠
    克隆类型
    • 27
    • 1
    单克隆
    标记
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    This UBXN6 antibody is un-conjugated
    应用范围
    • 23
    • 19
    • 18
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    特异性
    Detects only full length isoform
    交叉反应
    小鼠
    纯化方法
    purified
    免疫原
    recombinant protein purified from bacteria
    克隆位点
    2F8-24
    亚型
    IgG1
    Top Product
    Discover our top product UBXN6 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.5 % PBS, 50 % glycerol, 0.1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C
    储存方法
    short term: 2 °C - 8 °C, long term: -20 °C
  • 抗原
    UBXN6 (UBX Domain Protein 6 (UBXN6))
    别名
    UBXD1 (Full Length Isoform) (UBXN6 产品)
    别名
    Ubxd1 antibody, UBXD1 antibody, UBXDC2 antibody, 1200008L11Rik antibody, 2210415J11Rik antibody, AU040909 antibody, Ubxdc2 antibody, UBX domain protein 6 antibody, Ubxn6 antibody, UBXN6 antibody
    背景
    P97 is a highly abundant and conserved member of the AAA family of ATPase. It has been termed an ubiquitin selective chaperone as it functions within the ubiquitin and/or proteasome pathway. p97 does not interact with ubiquitinated substrates on its own, but requires specific adapters that interact with ubiquitinated substrates and p97 and recruits p97 to substrates. One family of adapters contains a UBX domain, which has been shown with certain adapters to function as a p97-binding module. UBXD1 is a UBX domain containing protein and p97 adapter. This adapter is unique in that it does not harbor an ubiquitin association domain and binds p97 via its PUG domain (another p97 binding motif). Two isoforms of UBXD1 are produced in cells, a full-length form of approximately 54 kDa, and an alternatively spliced variant that lacks the amino-terminal translational start site, and encodes a 47 kDa protein that is derived from an internal translational initiation site. UBXD1 expression at the RNA level has been shown to trend lower in poor prognostic cancers, including those of the breast and prostate.
    UniProt
    Q9BZV1
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