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VCAM1 抗体 (FITC)

This anti-VCAM1 antibody is a 小鼠 单克隆 antibody detecting VCAM1 in FACS. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN135717
发货至: 中国

Quick Overview for VCAM1 抗体 (FITC) (ABIN135717)

抗原

See all VCAM1 抗体
VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This VCAM1 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

1-G11B1
  • 特异性

    Human/Porcine CD106, Mr 110 kDa

    产品特性

    Mouse Anti-Human CD106-FITC

    免疫原

    Unknown

    亚型

    IgG1
  • 应用备注

    • Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB-NR - Reported in literature , ELISA - Reported in literature , Block - Reported in literature , Adhesion - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, and PE conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    限制

    仅限研究用
  • 缓冲液

    100 tests in 1.0 mL of PBS/Sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • Silva-Pedrosa, Campos, Fernandes, Silva, Calçada, Marote, Martinho, Veiga, Rodrigues, Salgado, Ferreira: "Cerebral Malaria Model Applying Human Brain Organoids." in: Cells, Vol. 12, Issue 7, (2023) (PubMed).

  • 抗原

    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

    别名

    CD106

    背景

    CD106, also known as INCAM-1, is a 100-110 kDa vascular adhesion cell adhesion molecule-1 (VCAM-1) that is member of the immunoglobulin superfamily. CD106 is expressed predominantly on cytokine-activated vascular endothelium but has also been identified on interfollicular dendritic cells, some macrophages and bone marrow stromal cells. Endothelial CD106 binds the integrins 41 (CD49d/CD29, VLA-4) and 47 and contributes to extravasation of lymphocytes, monocytes, basophils and eosinophils (but not neutrophils) from blood vessels, particularly at sites of inflammation. Unlike the 2 integrins, the CD106-VLA-4 interaction can mediate both the initial tethering and rolling of lymphocytes on endothelium as well as their subsequent arrest and firm adhesion. CD106 expressed on non-vascular tissues has been implicated in the interaction of hematopoietic progenitors with bone marrow stromal cells, B cell binding to follicular dendritic cells, costimulation of T cells, and embryonic development.

    途径

    Carbohydrate Homeostasis
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