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CD8 alpha 抗体 (PE)

This anti-CD8 alpha antibody is a 小鼠 单克隆 antibody detecting CD8 alpha in FACS. Suitable for 小鸡. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN135515
发货至: 中国

Quick Overview for CD8 alpha 抗体 (PE) (ABIN135515)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

适用

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小鸡

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD8 alpha antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

CT-8
  • 特异性

    Chicken/Turkey/Guinea Fowl/Pigeon CD8α, Mr 34 kDa

    产品特性

    Mouse Anti-Chicken CD8a-PE

    纯化方法

    Ion exchange column

    免疫原

    Chicken thymocytes and Ig-negative blood leukocytes

    亚型

    IgG1
  • 应用备注

    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, AF488, and PACBLU conjugates 1 g/106 cells PE and CY5 conjugates 0.2 g/106 cells APC, SPRD, AF647, and AF700 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • Han, Renu, Patil, Schrock, Feliciano-Ruiz, Selvaraj, Renukaradhya: "Immune Response to Salmonella Enteritidis Infection in Broilers Immunized Orally With Chitosan-Based Salmonella Subunit Nanoparticle Vaccine." in: Frontiers in immunology, Vol. 11, pp. 935, (2020) (PubMed).

    Peng, Yu, Liang, Chi, Li, Jiang, Fang, Cui, Lai, Zhou, Zhou: "The mitochondrial and death receptor pathways involved in the thymocytes apoptosis induced by aflatoxin B1." in: Oncotarget, Vol. 7, Issue 11, pp. 12222-34, (2017) (PubMed).

    Peng, Zhang, Bai, Ding, Zeng, Yang, Fang, Chen: "Histological lesions, cell cycle arrest, apoptosis and T cell subsets changes of spleen in chicken fed aflatoxin-contaminated corn." in: International journal of environmental research and public health, Vol. 11, Issue 8, pp. 8567-80, (2015) (PubMed).

    Chen, Peng, Fang, Cui, Zuo, Deng, Chen, Geng, Lai, Tang, Yang: "Effects of dietary selenium on histopathological changes and T cells of spleen in broilers exposed to aflatoxin B1." in: International journal of environmental research and public health, Vol. 11, Issue 2, pp. 1904-13, (2015) (PubMed).

  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8a

    背景

    CD8 In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two chains, and (ii) a heterodimer of an chain and a chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8- and CD8-chains, a relatively large proportion of the CD8+ TCR- cells in the spleens of embryos and young chicks express only the -chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR- CD8 cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80 % of thymocytes, 15 % of blood mononuclear cells and 50 % of spleen cells, but < 1 % of cells in the bursa and bone marrow.

    途径

    TCR Signaling
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