CD8 alpha 抗体 (PE)
Quick Overview for CD8 alpha 抗体 (PE) (ABIN135515)
抗原
See all CD8 alpha (CD8A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Chicken/Turkey/Guinea Fowl/Pigeon CD8α, Mr 34 kDa
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产品特性
- Mouse Anti-Chicken CD8a-PE
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纯化方法
- Ion exchange column
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免疫原
- Chicken thymocytes and Ig-negative blood leukocytes
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亚型
- IgG1
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应用备注
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry FITC, BIOT, AF488, and PACBLU conjugates 1 g/106 cells PE and CY5 conjugates 0.2 g/106 cells APC, SPRD, AF647, and AF700 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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样本量
- 1 mL
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- 0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C
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: "Immune Response to Salmonella Enteritidis Infection in Broilers Immunized Orally With Chitosan-Based Salmonella Subunit Nanoparticle Vaccine." in: Frontiers in immunology, Vol. 11, pp. 935, (2020) (PubMed).
: "The mitochondrial and death receptor pathways involved in the thymocytes apoptosis induced by aflatoxin B1." in: Oncotarget, Vol. 7, Issue 11, pp. 12222-34, (2017) (PubMed).
: "Histological lesions, cell cycle arrest, apoptosis and T cell subsets changes of spleen in chicken fed aflatoxin-contaminated corn." in: International journal of environmental research and public health, Vol. 11, Issue 8, pp. 8567-80, (2015) (PubMed).
: "Effects of dietary selenium on histopathological changes and T cells of spleen in broilers exposed to aflatoxin B1." in: International journal of environmental research and public health, Vol. 11, Issue 2, pp. 1904-13, (2015) (PubMed).
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: "Immune Response to Salmonella Enteritidis Infection in Broilers Immunized Orally With Chitosan-Based Salmonella Subunit Nanoparticle Vaccine." in: Frontiers in immunology, Vol. 11, pp. 935, (2020) (PubMed).
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- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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别名
- CD8a
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背景
- CD8 In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two chains, and (ii) a heterodimer of an chain and a chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8- and CD8-chains, a relatively large proportion of the CD8+ TCR- cells in the spleens of embryos and young chicks express only the -chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR- CD8 cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80 % of thymocytes, 15 % of blood mononuclear cells and 50 % of spleen cells, but < 1 % of cells in the bursa and bone marrow.
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途径
- TCR Signaling
抗原
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