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CD86 抗体

This anti-CD86 antibody is a 大鼠 单克隆 antibody detecting CD86 in FACS. Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN135273
发货至: 中国

Quick Overview for CD86 抗体 (ABIN135273)

抗原

See all CD86 抗体
CD86

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD86 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

GL1
  • 特异性

    Mouse CD86, Mr 80 kDa

    产品特性

    Rat Anti-Mouse CD86-UNLB

    纯化方法

    Purified

    免疫原

    LPS-activated CBA/Ca mouse spleen B cells

    亚型

    IgG2a
  • 应用备注

    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE, APC, SPRD, PE/CY7, AF647, and AF700 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    说明

    In vivo and in vitro blocking assays

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

    储存液

    Without preservative

    注意事项

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • Ma, Martínez-Ramírez, Borders, Gao, Sosa-Pineda: "Metabolic and non-metabolic liver zonation is established non-synchronously and requires sinusoidal Wnts." in: eLife, Vol. 9, (2020) (PubMed).

  • 抗原

    CD86

    别名

    CD86

    背景

    CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B-cell specific stimuli with peak expression at 18-42 hours after stimulation. CD86, along with CD80/B7-1, is an important accessory molecule in T cell costimulation via its interaction with CD28 and CD152/CTLA-4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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