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Transferrin Receptor 抗体

TFRC 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal RI7217 unconjugated
产品编号 ABIN135263
发货至: 中国
  • 抗原 See all Transferrin Receptor (TFRC) 抗体
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    适用
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    小鼠
    宿主
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    大鼠
    克隆类型
    • 141
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    单克隆
    标记
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    This Transferrin Receptor antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Mouse CD71, Mr 95 kDa
    产品特性
    Rat Anti-Mouse CD71-LE/AF
    纯化方法
    Protein A
    内毒素水平
    Low endotoxin
    免疫原
    DMSO induced Friend erythroleukemia 745.6
    克隆位点
    RI7217
    亚型
    IgG2a
    Top Product
    Discover our top product TFRC Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature , Sep - Reported in literature , Drug Delivery - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    储存液
    Azide free
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    -20 °C
    储存方法
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • 抗原
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    别名
    CD71 (TFRC 产品)
    别名
    Trfr antibody, LOC100219280 antibody, tfr antibody, cd71 antibody, tfr1 antibody, trfr antibody, CD71 antibody, T9 antibody, TFR antibody, TFR1 antibody, TR antibody, TRFR antibody, p90 antibody, 2610028K12Rik antibody, AI195355 antibody, AI426448 antibody, AU015758 antibody, E430033M20Rik antibody, Mtvr-1 antibody, Mtvr1 antibody, transferrin receptor antibody, TFRC antibody, Tfrc antibody, tfrc antibody
    背景
    CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens, presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor chain.
    途径
    Transition Metal Ion Homeostasis
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