Transferrin Receptor 抗体
Our Local Distributor
北京 101111
Quick Overview for Transferrin Receptor 抗体 (ABIN135263)
抗原
See all Transferrin Receptor (TFRC) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Rat Anti-Mouse CD71-LE/AF
-
特异性
- Mouse CD71, Mr 95 kDa
-
产品特性
- Low Endotoxin/Azide Free Anti-Mouse CD71 antibody for use in flow cytometry, immunocytochemistry, western blotting, immunoprecipitation, blocking, separation, and drug delivery assays.
-
内毒素水平
- Low Endotoxin
-
免疫原
- DMSO induced Friend erythroleukemia 745.6
-
亚型
- IgG2a
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Phosphate buffered saline, pH 7.4
-
储存液
- Azide free
-
注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
-
储存条件
- 4 °C
-
储存方法
- 2-8°C
-
-
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
-
别名
- CD71
-
背景
- CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens, presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor chain.
-
基因ID
- 22042
-
UniProt
- Q62351
-
途径
- Transition Metal Ion Homeostasis
抗原
-