Transferrin Receptor 抗体
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- 抗原 See all Transferrin Receptor (TFRC) 抗体
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This Transferrin Receptor antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Mouse CD71, Mr 95 kDa
- 产品特性
- Rat Anti-Mouse CD71-LE/AF
- 纯化方法
- Protein A
- 内毒素水平
- Low endotoxin
- 免疫原
- DMSO induced Friend erythroleukemia 745.6
- 克隆位点
- RI7217
- 亚型
- IgG2a
- Top Product
- Discover our top product TFRC Primary Antibody
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- 应用备注
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- Applications: FC - Quality tested , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature , Sep - Reported in literature , Drug Delivery - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- 样本量
- 1 mL
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- 0.5 mg of purified immunoglobulin in 1.0 mL of PBS
- 储存液
- Azide free
- 注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- 储存条件
- -20 °C
- 储存方法
- Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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- 抗原
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- 别名
- CD71 (TFRC 产品)
- 背景
- CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens, presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor chain.
- 途径
- Transition Metal Ion Homeostasis
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