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Transferrin Receptor 抗体 (PE)

This anti-Transferrin Receptor antibody is a 大鼠 单克隆 antibody detecting Transferrin Receptor in FACS. Suitable for 小鼠.
产品编号 ABIN135262
发货至: 中国

Quick Overview for Transferrin Receptor 抗体 (PE) (ABIN135262)

抗原

See all Transferrin Receptor (TFRC) 抗体
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This Transferrin Receptor antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

RI7217
  • 特异性

    Mouse CD71, Mr 95 kDa

    产品特性

    Rat Anti-Mouse CD71-PE

    纯化方法

    Ion exchange

    免疫原

    DMSO induced Friend erythroleukemia 745.6

    亚型

    IgG2a
  • 应用备注

    • Applications: FC - Quality tested , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature , Sep - Reported in literature , Drug Delivery - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • 抗原

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    别名

    CD71

    背景

    CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens, presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor chain.

    途径

    Transition Metal Ion Homeostasis
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