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CD22 抗体

CD22 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 2D6 unconjugated
产品编号 ABIN135163
发货至: 中国
  • 抗原 See all CD22 抗体
    CD22 (CD22 Molecule (CD22))
    适用
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    小鼠
    宿主
    • 97
    • 61
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    大鼠
    克隆类型
    • 119
    • 54
    单克隆
    标记
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    This CD22 antibody is un-conjugated
    应用范围
    • 108
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    Flow Cytometry (FACS)
    特异性
    Mouse CD22, Mr 150 kDa
    产品特性
    Rat Anti-Mouse CD22-LE/AF
    内毒素水平
    Low endotoxin
    免疫原
    Splenic lymphocyte plasma membranes from CBA x C57 F1 mice
    克隆位点
    2D6
    亚型
    IgG1
    Top Product
    Discover our top product CD22 Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Activ - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    储存液
    Azide free
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    -20 °C
    储存方法
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • 抗原
    CD22 (CD22 Molecule (CD22))
    别名
    CD22 (CD22 产品)
    别名
    A530093D23 antibody, Lyb-8 antibody, Lyb8 antibody, SIGLEC-2 antibody, SIGLEC2 antibody, siglec-2 antibody, CD22 antigen antibody, CD22 molecule antibody, Cd22 antibody, CD22 antibody
    背景
    CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage), appears on the cell surface concomitant with IgD, and is found on most IgM+IgD+ mature B lymphocytes. Expression is lost with terminal differentiation of B cells and is absent on plasma cells. Activation of B cells via cross-linking of surface Ig increases CD22 expression. CD22 associates with the B cell receptor (BCR) complex and mediates intercellular adhesion. Its intracellular domain is phosphorylated after antigen receptor cross-linking and is involved in negative regulation of B-cell activation.
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