CD19 抗体
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北京 101111
Quick Overview for CD19 抗体 (ABIN135152)
抗原
See all CD19 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Rat Anti-Mouse CD19-LE/AF
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特异性
- Mouse CD19, Mr 95 kDa
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产品特性
- Low Endotoxin/Azide Free Anti-Mouse CD19 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, and separation assays.
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内毒素水平
- Low Endotoxin
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免疫原
- Mouse CD19-expressing K562 human erythroleukemia cells
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered saline, pH 7.4
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储存液
- Azide free
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注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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储存条件
- 4 °C
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储存方法
- 2-8°C
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- CD19 (CD19 Molecule (CD19))
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别名
- CD19
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背景
- CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Recent studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow.
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基因ID
- 12478
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UniProt
- P25918
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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