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CD19 抗体

The 大鼠 单克隆 anti-CD19 antibody is suitable to detect CD19 in samples from 小鼠. It has been validated for FACS, IP, IHC (fro) 和 Sep.
产品编号 ABIN135152
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD19 抗体 (ABIN135152)

抗原

See all CD19 抗体
CD19 (CD19 Molecule (CD19))

适用

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小鼠

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大鼠

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单克隆

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This CD19 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Separation (Sep)

克隆位点

6D5
  • 原理

    Rat Anti-Mouse CD19-LE/AF

    特异性

    Mouse CD19, Mr 95 kDa

    产品特性

    Low Endotoxin/Azide Free Anti-Mouse CD19 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, and separation assays.

    内毒素水平

    Low Endotoxin

    免疫原

    Mouse CD19-expressing K562 human erythroleukemia cells

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Phosphate buffered saline, pH 7.4

    储存液

    Azide free

    注意事项

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    2-8°C
  • 抗原

    CD19 (CD19 Molecule (CD19))

    别名

    CD19

    背景

    CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Recent studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow.

    基因ID

    12478

    UniProt

    P25918

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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