CD19 抗体 (Biotin)
Quick Overview for CD19 抗体 (Biotin) (ABIN135149)
抗原
See all CD19 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            特异性
- Mouse CD19, Mr 95 kDa
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                                            产品特性
- Rat Anti-Mouse CD19-BIOT
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                                            免疫原
- Mouse CD19-expressing K562 human erythroleukemia cells
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                                            亚型
- IgG2a
 
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                                            应用备注
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                        - Applications: FC - Quality tested , IHC-FS - Reported in literature , IP , Sep - Reported in literature
- Working Dilutions: Flow Cytometry FITC, BIOT and AF488 conjugates 1 g/106 cells PE, APC, SPRD, CY5, PE/CY5.5 and PE/CY7 conjugates 0.2 g/106 cells PACBLU conjugate 0.3 g/106 cells AF647 and AF700 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
 
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                                            说明
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                        In vivo and in vitro functional studies 
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                                            样本量
- 1 mL
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                                            限制
- 仅限研究用
 
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                                            浓度
- 0.5 mg/mL
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                                            缓冲液
- 0.5 mg in 1.0 mL of PBS/Sodium azide
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
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                         Protect conjugated products from light. 
 Each reagent is stable for the period shown on the bottle label if stored as directed.
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                                            储存条件
- 4 °C
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                                            储存方法
- Store at 2-8°C
 
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    - CD19 (CD19 Molecule (CD19))
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                                            别名
- CD19
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                                            背景
- CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Recent studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow.
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                                            途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
 抗原
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