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ITGA4 抗体 (FITC)

ITGA4 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal PS-2 FITC
产品编号 ABIN135076
发货至: 中国
  • 抗原 See all ITGA4 抗体
    ITGA4 (Integrin alpha 4 (ITGA4))
    适用
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    小鼠
    宿主
    • 81
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    • 34
    大鼠
    克隆类型
    • 97
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    单克隆
    标记
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    This ITGA4 antibody is conjugated to FITC
    应用范围
    • 99
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    Flow Cytometry (FACS)
    特异性
    Mouse/Human CD49d, Mr 150 kDa
    产品特性
    Rat Anti-Mouse CD49d-FITC
    免疫原
    P815 cells
    克隆位点
    PS-2
    亚型
    IgG2b
    Top Product
    Discover our top product ITGA4 Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Adhesion - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg in 1.0 mL of PBS/Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • 抗原
    ITGA4 (Integrin alpha 4 (ITGA4))
    别名
    CD49d (ITGA4 产品)
    别名
    CD49D antibody, IA4 antibody, LOC100219853 antibody, integrin subunit alpha 4 antibody, integrin alpha 4 antibody, integrin subunit alpha 4 S homeolog antibody, ITGA4 antibody, Itga4 antibody, itga4.S antibody
    背景
    CD49d, the 4 chain (100 kDa) of the VLA-4 integrin heterodimer (Mr 150 kDa) VLA-4 belongs to the 1-integrin family, which functions both as cell-matrix and cell-cell receptors.1-3 As a matrix receptor VLA-4 binds to an alternatively spliced domain of fibronectin, while as a cellular receptor it associates with its counter-receptor ligand VCAM-1. In addition to CD44/pgp-1, VLA-4 has been shown to be important for lymphopoiesis, and is also believed to be important for extravasation of lymphocytes into sites of inflammation as a second signal in addition to LFA/ICAM-1. CD49d/VLA-4 is expressed in low amounts on resting lymphocytes and monocytes, is absent or minimally detectable on stromal cells, whereas virtually all lymphoid and myeloid cells in bone marrow and in long-term culture are positive.
    途径
    Integrin Complex
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