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ITGA4 抗体

ITGA4 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal PS-2 unconjugated
产品编号 ABIN135075
发货至: 中国
  • 抗原 See all ITGA4 抗体
    ITGA4 (Integrin alpha 4 (ITGA4))
    适用
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    小鼠
    宿主
    • 80
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    • 34
    大鼠
    克隆类型
    • 96
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    • 1
    单克隆
    标记
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    This ITGA4 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Mouse/Human CD49d, Mr 150 kDa
    产品特性
    Rat Anti-Mouse CD49d-UNLB
    纯化方法
    Purified
    免疫原
    P815 cells
    克隆位点
    PS-2
    亚型
    IgG2b
    Top Product
    Discover our top product ITGA4 Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Adhesion - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    储存液
    Without preservative
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • 抗原
    ITGA4 (Integrin alpha 4 (ITGA4))
    别名
    CD49d (ITGA4 产品)
    别名
    CD49D antibody, IA4 antibody, LOC100219853 antibody, integrin subunit alpha 4 antibody, integrin alpha 4 antibody, integrin subunit alpha 4 S homeolog antibody, ITGA4 antibody, Itga4 antibody, itga4.S antibody
    背景
    CD49d, the 4 chain (100 kDa) of the VLA-4 integrin heterodimer (Mr 150 kDa) VLA-4 belongs to the 1-integrin family, which functions both as cell-matrix and cell-cell receptors.1-3 As a matrix receptor VLA-4 binds to an alternatively spliced domain of fibronectin, while as a cellular receptor it associates with its counter-receptor ligand VCAM-1. In addition to CD44/pgp-1, VLA-4 has been shown to be important for lymphopoiesis, and is also believed to be important for extravasation of lymphocytes into sites of inflammation as a second signal in addition to LFA/ICAM-1. CD49d/VLA-4 is expressed in low amounts on resting lymphocytes and monocytes, is absent or minimally detectable on stromal cells, whereas virtually all lymphoid and myeloid cells in bone marrow and in long-term culture are positive.
    途径
    Integrin Complex
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