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VCAM1 抗体

VCAM1 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal M-K-2 unconjugated
产品编号 ABIN135074
发货至: 中国
  • 抗原 See all VCAM1 抗体
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    适用
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    小鼠
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    大鼠
    克隆类型
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    单克隆
    标记
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    This VCAM1 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Mouse CD106, Mr 100-110 kDa
    产品特性
    Rat Anti-Mouse CD106-LE/AF
    内毒素水平
    Low endotoxin
    免疫原
    BALB/3T3 and +/+2.4 cells
    克隆位点
    M-K-2
    亚型
    IgG1
    Top Product
    Discover our top product VCAM1 Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , WB - Reported in literature , Adhesion - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    储存液
    Azide free
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    -20 °C
    储存方法
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • Gilchrist, Kinchesh, Zarghami, Khrapitchev, Sibson, Kersemans, Smart: "Improved detection of molecularly targeted iron oxide particles in mouse brain using B0 field stabilised high resolution MRI." in: Magnetic resonance imaging, Vol. 67, pp. 101-108, (2020) (PubMed).

    Zarghami, Khrapitchev, Perez-Balderas, Soto, Larkin, Bau, Sibson: "Optimization of molecularly targeted MRI in the brain: empirical comparison of sequences and particles." in: International journal of nanomedicine, Vol. 13, pp. 4345-4359, (2018) (PubMed).

  • 抗原
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    别名
    CD106 (VCAM1 产品)
    别名
    CD106 antibody, INCAM-100 antibody, Vcam-1 antibody, VCAM1B antibody, fi76d06 antibody, wu:fi76d06 antibody, zgc:158875 antibody, VCAM1 antibody, vascular cell adhesion molecule 1 antibody, vascular cell adhesion molecule 1b antibody, VCAM1 antibody, Vcam1 antibody, vcam1b antibody, VCAM-1 antibody
    背景
    VCAM-1 is an adhesion molecule and a major mediator of the inflammatory response. It is expressed on activated microvascular endothelial cells in response to signals arising from immune responses in infection, graft rejection, tumor recognition and killing. The complementary binding ligand for VCAM-1 is VLA-4/CD49d. In addition to VCAM-1, VLA-4 also recognizes the extracellular matrix molecule fibronectin. This pairing of VCAM-1 and VLA-4 is able to provide a second signal (i.e., non-antigen specific) for T cell stimulation, such as that seen in transplantation. The monoclonal antibody MK-2 has been used in transplant studies to suppress cardiac rejection and induce long-term cardiac graft survival. In addition to inflammatory responses, VCAM-1 has a significant role in hemopoiesis through its ability to retain lymphocyte and myeloid precursors on stromal cells in the marrow and lymphoid organs. CD106/VCAM-1 exists as an integral membrane protein.
    途径
    Carbohydrate Homeostasis
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