VCAM1 抗体
(3 references)Quick Overview for VCAM1 抗体 (ABIN135070)
抗原
See all VCAM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Mouse CD106, Mr 100-110 kDa
-
产品特性
- Rat Anti-Mouse CD106-UNLB
-
纯化方法
- Purified
-
免疫原
- BALB/3T3 and +/+2.4 cells
-
亚型
- IgG1
-
-
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 1-739) antibody
VCAM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 1-739) antibodyVCAM1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) antibodyVCAM1 适用: 人, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3H10 unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 25-183) antibodyVCAM1 适用: 人, 大鼠, 猴 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 6A11D8 unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 109-318) antibodyVCAM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 300-400) antibodyVCAM1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) antibodyVCAM1 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 6G9 unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 511-682) antibodyVCAM1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 369-658) antibodyVCAM1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vascular Cell Adhesion Molecule 1 (VCAM1) (AA 409-682) antibodyVCAM1 适用: 兔 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 3-2# unconjugated
-
-
应用备注
-
- Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , WB - Reported in literature , Adhesion - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
-
样本量
- 1 mL
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
-
储存液
- Without preservative
-
注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
-
储存条件
- 4 °C
-
储存方法
- Store at 2-8°C
-
-
-
: "Ablation of endothelial Pfkfb3 protects mice from acute lung injury in LPS-induced endotoxemia." in: Pharmacological research, Vol. 146, pp. 104292, (2020) (PubMed).
: "Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation." in: Nature communications, Vol. 8, Issue 1, pp. 943, (2018) (PubMed).
: "Soluble Epoxide Hydrolase in Hydrocephalus, Cerebral Edema, and Vascular Inflammation After Subarachnoid Hemorrhage." in: Stroke, Vol. 46, Issue 7, pp. 1916-22, (2015) (PubMed).
-
: "Ablation of endothelial Pfkfb3 protects mice from acute lung injury in LPS-induced endotoxemia." in: Pharmacological research, Vol. 146, pp. 104292, (2020) (PubMed).
-
- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
-
别名
- CD106
-
背景
- VCAM-1 is an adhesion molecule and a major mediator of the inflammatory response. It is expressed on activated microvascular endothelial cells in response to signals arising from immune responses in infection, graft rejection, tumor recognition and killing. The complementary binding ligand for VCAM-1 is VLA-4/CD49d. In addition to VCAM-1, VLA-4 also recognizes the extracellular matrix molecule fibronectin. This pairing of VCAM-1 and VLA-4 is able to provide a second signal (i.e., non-antigen specific) for T cell stimulation, such as that seen in transplantation. The monoclonal antibody MK-2 has been used in transplant studies to suppress cardiac rejection and induce long-term cardiac graft survival. In addition to inflammatory responses, VCAM-1 has a significant role in hemopoiesis through its ability to retain lymphocyte and myeloid precursors on stromal cells in the marrow and lymphoid organs. CD106/VCAM-1 exists as an integral membrane protein.
-
途径
- Carbohydrate Homeostasis
抗原
-
